COMPOSITIONS WITH CONTROLLED DRUG RELEASE

Title:

COMPOSITIONS WITH CONTROLLED DRUG RELEASE

Document Type and Number:

WIPO Patent Application WO/2002/066004

Kind Code:

A1

Abstract:

Compositions with controlled drug release comprising a water-soluble polymer, an enteric polymer, an additive showing an alkaline pH value when suspended or dissolved in water and a drug. From these compositions, a drug can be hardly eluted in the stomach but released under control in the lower parts of the digestive tracts (lower part of the small intestine, the large intestine, etc.) while not so largely affected by pH changes. Thus, these compositions are characterized by being capable of delivering a drug selectively to the lower part of the small intestine and the large intestine.

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Inventors:

OMURA TOMOYUKI (JP)
SAMEMOTO HIROFUMI (JP)
INOUE TADAAKI (JP)

Application Number:

PCT/JP2002/001634

Publication Date:

August 29, 2002

Filing Date:

February 22, 2002

Export Citation:

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Assignee:

MITSUBISHI PHARMA CORP (JP)
OMURA TOMOYUKI (JP)
SAMEMOTO HIROFUMI (JP)
INOUE TADAAKI (JP)

International Classes:

A61K9/20; A61K9/32; (IPC1-7): A61K9/00; A61K9/28; A61K9/32; A61K47/32

Foreign References:

JPH11286438A	1999-10-19
JPH0826977A	1996-01-30
JPH08143476A	1996-06-04
EP0043877A1	1982-01-20
EP0386967A2	1990-09-12

Attorney, Agent or Firm:

Takashima, Hajime (2-14 Fushimimachi 4-chome, Chuo-k, Osaka-shi Osaka, JP)

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