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Patent Searching and Data


Title:
COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES
Document Type and Number:
WIPO Patent Application WO2005115444
Kind Code:
A3
Abstract:
Antiviral compositions comprising a modified nuclease, or a plurality of such modified nucleases having at least one non-natural amino acid residue substituted for a naturally occurring amino acid in a parent nuclease are provided, as are methods of use and kits providing unit dosages of such compositions.

Inventors:
SALGANIK RUDOLF I (US)
APPELBAUM JACOB G (US)
Application Number:
PCT/US2005/012532
Publication Date:
December 14, 2006
Filing Date:
April 14, 2005
Export Citation:
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Assignee:
AVIRID INC (US)
SALGANIK RUDOLF I (US)
APPELBAUM JACOB G (US)
International Classes:
C12N9/22; A61K38/46; C07H21/04
Foreign References:
US5989886A1999-11-23
Other References:
NOREN C.J. ET AL.: "A General Method for Site-specific Incorporation of Unnatural Amino Acids into Proteins", SCIENCE, vol. 244, 1989, pages 182 - 188, XP002925217
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