Title:
COMPOUND AND ASYMMETRIC SYNTHESIS REACTION
Document Type and Number:
WIPO Patent Application WO/2013/088972
Kind Code:
A1
Abstract:
Provided is a compound represented by general formula (1). (1) In general formula (1), R1 is either a protecting group for a hydroxyl group or a hydrogen atom. R2 is either a methyl group or an ethyl group.
Inventors:
SHIBASAKI MASAKATSU (JP)
KUMAGAI NAOYA (JP)
KUMAGAI NAOYA (JP)
Application Number:
PCT/JP2012/081042
Publication Date:
June 20, 2013
Filing Date:
November 30, 2012
Export Citation:
Assignee:
MICROBIAL CHEM RES FOUND (JP)
International Classes:
C07D307/33; B01J31/24; C07C323/12; C07C381/12; C07D301/02; C07D303/22; C07D309/30; C07B53/00; C07B61/00
Domestic Patent References:
| WO2004071503A1 | 2004-08-26 | |||
| WO2004071503A1 | 2004-08-26 |
Foreign References:
| US5693847A | 1997-12-02 | |||
| JP2002275127A | 2002-09-25 |
Other References:
SHO TAKECHI ET AL.: "A Direct Catalytic Asymmetric Aldol Reaction of a-Sulfanyl Lactones:Efficient Synthesis of SPT Inhibitors", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 51, no. 17, 23 April 2012 (2012-04-23), pages 4218 - 4222, XP055154890
SHO TAKECHI ET AL.: "a-thiolactone o Kyukakuzai to suru Diastereo Sentakuteki Shokubaiteki Fusei Direct Aldol Hanno", THE PHARMACEUTICAL SOCIETY OF JAPAN DAI 132 NENKAI YOSHISHU 2, 5 March 2012 (2012-03-05), pages 154, XP008174096
TOMOYUKI ESUMI ET AL.: "Synthesis of Viridiofungin A and its Absolute Structure", DAI 39 KAI SYMPOSIUM ON THE CHEMISTRY OF NATURAL PRODUCTS, SYMPOSIUM PAPERS, 20 July 1997 (1997-07-20), pages 409 - 414, XP002985348
BARRY M. TROST ET AL.: "A synthetic approach to polyene macrolldes: Synthesis of the building blocks", TETRAHEDRON LETTERS, vol. 27, no. 47, 1986, pages 5691 - 5694, XP002976252
KAZUHIKO TANAKA ET AL.: "New Methods for Stereoselective Synthesis of a-Alkylidene-y- butyrolactones Using Monoanion of O-Ethyl S-(Tetrahydro-2-oxo-3-furanyl) Thiocarbonate and Dianion of a-Mercapto-y-butyrolactone", BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, vol. 53, no. 10, 1980, pages 2910 - 2916, XP008174050
SAKAMOTO, H.; OKAMOTO, K. ET AL., NAT. CHEM. BIOL., vol. 1, 2005, pages 333 - 337
GREEN ET AL.: "Protective Groups in Organic Synthesis", 1999, JOHN WILEY & SONS, INC
BARRY M. TROST; HENRY. C. ARDNT, J. ORG. CHEM., vol. 38, 1973, pages 3140 - 3144
AMOS B. SMITH, III; RICHARD J. FOX, ORG. LETT, vol. 6, 2004, pages 1477 - 1480
See also references of EP 2792675A4
SHO TAKECHI ET AL.: "a-thiolactone o Kyukakuzai to suru Diastereo Sentakuteki Shokubaiteki Fusei Direct Aldol Hanno", THE PHARMACEUTICAL SOCIETY OF JAPAN DAI 132 NENKAI YOSHISHU 2, 5 March 2012 (2012-03-05), pages 154, XP008174096
TOMOYUKI ESUMI ET AL.: "Synthesis of Viridiofungin A and its Absolute Structure", DAI 39 KAI SYMPOSIUM ON THE CHEMISTRY OF NATURAL PRODUCTS, SYMPOSIUM PAPERS, 20 July 1997 (1997-07-20), pages 409 - 414, XP002985348
BARRY M. TROST ET AL.: "A synthetic approach to polyene macrolldes: Synthesis of the building blocks", TETRAHEDRON LETTERS, vol. 27, no. 47, 1986, pages 5691 - 5694, XP002976252
KAZUHIKO TANAKA ET AL.: "New Methods for Stereoselective Synthesis of a-Alkylidene-y- butyrolactones Using Monoanion of O-Ethyl S-(Tetrahydro-2-oxo-3-furanyl) Thiocarbonate and Dianion of a-Mercapto-y-butyrolactone", BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, vol. 53, no. 10, 1980, pages 2910 - 2916, XP008174050
SAKAMOTO, H.; OKAMOTO, K. ET AL., NAT. CHEM. BIOL., vol. 1, 2005, pages 333 - 337
GREEN ET AL.: "Protective Groups in Organic Synthesis", 1999, JOHN WILEY & SONS, INC
BARRY M. TROST; HENRY. C. ARDNT, J. ORG. CHEM., vol. 38, 1973, pages 3140 - 3144
AMOS B. SMITH, III; RICHARD J. FOX, ORG. LETT, vol. 6, 2004, pages 1477 - 1480
See also references of EP 2792675A4
Attorney, Agent or Firm:
HIROTA, Koichi et al. (JP)
Koichi Hirota (JP)
Koichi Hirota (JP)
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Claims: