COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME

Title:

COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME

Document Type and Number:

WIPO Patent Application WO/2024/005460

Kind Code:

A1

Abstract:

The present invention provides a compound comprising a self-immolative group and a ligand-drug conjugate comprising same. According to the present invention, an active material may be stably delivered up to a target site, and the active material may be rapidly released at the target site, thereby increasing the efficacy of the active material, and the active material may be inhibited from causing a side effect at a location other than the target location.

More Like This:

JP2023502182	Formulated and/or co-formulated liposomal compositions containing IDO antagonist prodrugs useful in the treatment of cancer and methods thereof
WO/1997/024111	NOVEL HYALURONIC ACID RECEPTORS BINDING AGENTS AND THE USE THEREOF
JP6340019	Pyrrolobenzodiazepines and their conjugates

Inventors:

WOO SUNG HO (KR)
PARK SU HO (KR)
CHO JONG UN (KR)
YUN SANG HYEON (KR)
MIN GYOUNG WOOK (KR)
PARK OK KU (KR)
LEE HYUN MI (KR)

Application Number:

PCT/KR2023/008742

Publication Date:

January 04, 2024

Filing Date:

June 23, 2023

Export Citation:

Click for automatic bibliography generation Help

Assignee:

TRIOAR INC (KR)

International Classes:

A61K47/54; A61K47/68; A61K49/00; A61P31/00; A61P35/00; A61P37/00; C07D409/14; C07H15/26; C07H17/02

Domestic Patent References:

WO2017197056A1	2017-11-16
WO2021016537A1	2021-01-28

Foreign References:

KR20180077087A	2018-07-06
US20140031535A1	2014-01-30

Other References:

SATO DAISUKE, WU ZHIYUAN, FUJITA HIKARU, LINDSEY JONATHAN: "Design, Synthesis, and Utility of Defined Molecular Scaffolds", ORGANICS, vol. 2, no. 3, 11 July 2021 (2021-07-11), pages 161 - 273, XP093122158, ISSN: 2673-401X, DOI: 10.3390/org2030013

Attorney, Agent or Firm:

RYU, Jong Woo et al. (KR)

Download PDF:

View/Download PDF PDF Help

Previous Patent: LAYERED GIRDER VENTILATION WINDOW SYSTEM

Next Patent: NOVEL LINKER COMPOUND AND LIGAND-DRUG CONJUGATE THEREFOR