Title:
COMPOUND CONTAINING DIPHENYLMETHANE STRUCTURE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/143392
Kind Code:
A1
Abstract:
Disclosed are a compound containing a diphenylmethane structure and a use thereof, belonging to the technical field of compound and polypeptide synthesis. The structure of the compound containing a diphenylmethane structure of the present invention is represented by general formula (1). The compound containing a diphenylmethane structure of the present invention contains a hydroxyl, an amino group, a substituted amino group, and an active group, and can be used as an amino acid or a peptide C-terminal protection reagent. A peptide synthesis reaction using this protection carrier has a fast reaction speed and a high reagent utilization rate in a suitable solvent system; post-treatment is carried out by means of simple liquid-liquid extraction separation, i.e. effective purification can be carried out, and finally, a product with a high purity can be obtained; and during a synthesis process, the change in solubility is small and an operation process has a strong universality, and therefore, the present method can be developed into a universal production method.
Inventors:
LIANG WEIZHOU (CN)
ZHENG QINGQUAN (CN)
TANG QI (CN)
ZHENG QINGQUAN (CN)
TANG QI (CN)
Application Number:
PCT/CN2019/125136
Publication Date:
July 16, 2020
Filing Date:
December 13, 2019
Export Citation:
Assignee:
GUANGZHOU TROJAN PHARMATEC LTD (CN)
International Classes:
C07C235/48
Foreign References:
| CN110194724A | 2019-09-03 | |||
| CN109678751A | 2019-04-26 | |||
| CN107406480A | 2017-11-28 | |||
| CN107011132A | 2017-08-04 | |||
| CN107011132A | 2017-08-04 |
Other References:
See also references of EP 3901132A4
Attorney, Agent or Firm:
JIAQUAN IP LAW FIRM (CN)
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