Title:
COMPOUND CONTAINING INDOLEACETIC ACID CORE STRUCTURE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/119643
Kind Code:
A1
Abstract:
Disclosed are a compound as shown by the following formula 1, and a pharmaceutically acceptable salt, an ester, a hydrate and an organic solvate thereof. In the formula (1), the groups R1 to R17 are independently selected from the group consisting of hydrogen, fluorine, chlorine, bromine, iodine, C1-C8 alkyl, C1-C8 alkoxy, carbonyl, hydroxyl, amino, azido, carboxyl and C1-C8 alkylsulfinyl, respectively; and X is a carbon or nitrogen atom; Y is selected from the following groups: a single bond, C1-C8 alkylene, C6-C20 arylene and C4-C20 heteroarylene; and n is an integer from 5 to 20. Also provided in the present invention are a pharmaceutical composition containing the compound, and a use thereof in the field of tumour therapy.
Inventors:
RAN RUIQIONG (CN)
Application Number:
PCT/CN2016/071934
Publication Date:
August 04, 2016
Filing Date:
January 25, 2016
Export Citation:
Assignee:
RAN RUIQIONG (CN)
International Classes:
C07D209/26; A61K31/216; A61K31/405; A61P29/00; A61P35/00; A61P35/02; C07C317/44
Domestic Patent References:
| WO2006099416A1 | 2006-09-21 |
Foreign References:
| CN104592091A | 2015-05-06 | |||
| CN1237162A | 1999-12-01 | |||
| US3654349A | 1972-04-04 |
Other References:
See also references of EP 3252039A4
Attorney, Agent or Firm:
SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC (CN)
上海专利商标事务所有限公司 (CN)
上海专利商标事务所有限公司 (CN)
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