Title:
COMPOUND, FLUOROCHROME, KIT, AND CELL DETECTION METHOD
Document Type and Number:
WIPO Patent Application WO/2022/230354
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a compound that can be suitably used in a fluorochrome or similar, a novel fluorochrome and kit for conveniently detecting cells, and a novel method for conveniently detecting cells or similar. A compound represented by formula (1) or a salt thereof. (In formula (1), R1 is a substituted or unsubstituted C1-12 alkyl group or similar, R2 and R3 are each independently a substituted or unsubstituted C1-6 alkyl group or similar, R4 and R5 are each independently a C1-12 alkyl group or similar, n is an integer from 1 to 4, and a and b are each independently an integer from 0 to 4.)
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Inventors:
NIKO YOSUKE (JP)
INOUE KAZUKI (JP)
NAKAYAMA TAKU (JP)
HADANO SHINGO (JP)
WATANABE SHIGERU (JP)
MURAKAMI MASAMOTO (JP)
KAWAKAMI RYOSUKE (JP)
TSUDA TERUKO (JP)
SAYAMA KOJI (JP)
IMAMURA TAKESHI (JP)
INOUE KAZUKI (JP)
NAKAYAMA TAKU (JP)
HADANO SHINGO (JP)
WATANABE SHIGERU (JP)
MURAKAMI MASAMOTO (JP)
KAWAKAMI RYOSUKE (JP)
TSUDA TERUKO (JP)
SAYAMA KOJI (JP)
IMAMURA TAKESHI (JP)
Application Number:
PCT/JP2022/008939
Publication Date:
November 03, 2022
Filing Date:
March 02, 2022
Export Citation:
Assignee:
UNIV NAT CORP KOCHI UNIV (JP)
UNIV NAT CORP EHIME UNIV (JP)
UNIV NAT CORP EHIME UNIV (JP)
International Classes:
C07D295/112; A61K51/04; C09B57/00; C09B67/20; C09K11/06; G01N33/48
Domestic Patent References:
| WO2022054755A1 | 2022-03-17 | |||
| WO2019093400A1 | 2019-05-16 |
Foreign References:
| JP2018201678A | 2018-12-27 |
Other References:
VALANCIUNAITE JURGA, KEMPF EMILIE, SEKI HITOMI, DANYLCHUK DMYTRO I., PEYRIÉRAS NADINE, NIKO YOSUKE, KLYMCHENKO ANDREY S.: "Polarity Mapping of Cells and Embryos by Improved Fluorescent Solvatochromic Pyrene Probe", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 92, no. 9, 5 May 2020 (2020-05-05), US , pages 6512 - 6520, XP055910804, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.0c00023
MAGGIO EMANUELE, TROISI ALESSANDRO: "An expression for the bridge-mediated electron transfer rate in dye-sensitized solar cells", PHILOSOPHICAL TRANSACTIONS A .MATHEMATICAL, PHYSICAL AND ENGINEERING SCIENCES, THE ROYAL SOCIETY, LONDON, GB, vol. 372, no. 2013, 13 April 2014 (2014-04-13), GB , pages 20130011, XP055982496, ISSN: 1364-503X, DOI: 10.1098/rsta.2013.0011
SUMALEKSHMY S., GOPIDAS K. R.: "Intramolecular charge transfer processes in donor-acceptor substituted vinyltetrahydropyrenes", PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, ROYAL SOCIETY OF CHEMISTRY , CAMBRIDGE, GB, vol. 4, no. 7, 1 July 2005 (2005-07-01), GB , pages 539 - 546, XP055982497, ISSN: 1474-905X, DOI: 10.1039/b503251b
Y. NIKKO ET AL., SCI, REP., 2016
CELL CHEM. BIOL., vol. 23, 2016, pages 137 - 157
LASER PHOTONICS REV, vol. 13, 2019, pages 1800292
CAS, no. 74515-25-6
MAGGIO EMANUELE, TROISI ALESSANDRO: "An expression for the bridge-mediated electron transfer rate in dye-sensitized solar cells", PHILOSOPHICAL TRANSACTIONS A .MATHEMATICAL, PHYSICAL AND ENGINEERING SCIENCES, THE ROYAL SOCIETY, LONDON, GB, vol. 372, no. 2013, 13 April 2014 (2014-04-13), GB , pages 20130011, XP055982496, ISSN: 1364-503X, DOI: 10.1098/rsta.2013.0011
SUMALEKSHMY S., GOPIDAS K. R.: "Intramolecular charge transfer processes in donor-acceptor substituted vinyltetrahydropyrenes", PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, ROYAL SOCIETY OF CHEMISTRY , CAMBRIDGE, GB, vol. 4, no. 7, 1 July 2005 (2005-07-01), GB , pages 539 - 546, XP055982497, ISSN: 1474-905X, DOI: 10.1039/b503251b
Y. NIKKO ET AL., SCI, REP., 2016
CELL CHEM. BIOL., vol. 23, 2016, pages 137 - 157
LASER PHOTONICS REV, vol. 13, 2019, pages 1800292
CAS, no. 74515-25-6
Attorney, Agent or Firm:
UNIUS PATENT ATTORNEYS OFFICE (JP)
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