Title:
COMPOUND FOR GENERATING SECOND HARMONIC OF LIGHT, DYE COMPOSITION FOR GENERATING SECOND HARMONIC OF LIGHT, AND CELL EXAMINATION METHOD
Document Type and Number:
WIPO Patent Application WO/2014/189145
Kind Code:
A1
Abstract:
Provided are a compound that generates an SHG signal but has suppressed generation of a TPF signal. Also provided is a cell examination method using the same. A compound for generating a second harmonic of light, the compound being an azobenzene derivative of formula (1), or a salt thereof. (R1 and R2 independently represent alkyl groups having 6-12 carbon atoms, and R3 to R18 independently represent substituents selected from hydrogen, halogens, alkyl groups, alkoxy groups, aryl groups, amino groups, hydroxyl groups, nitro groups, and cyano groups, but R5 and R6, R9 and R10, R13 and R14, and R17 and R18 may combine together and form a ring structure having 5-7 carbon atoms. X represents –N+R19R20R21, a sulfonyl group, a carboxyl group, or an –OR group. Here, R19, R20, and R21 independently represent straight-chain or branched alkyl groups having 1-5 carbon atoms, and –OR represents a monovalent polyalkylene oxide group terminated by an alkoxy group. a is 0 or 1, b is 0 or 1, and n is an integer of 1-10.)
Inventors:
NURIYA MUTSUO (JP)
YASUI MASATO (JP)
ARAI TATSUO (JP)
MOMOTAKE ATSUYA (JP)
FUKUSHIMA SYUN (JP)
YASUI MASATO (JP)
ARAI TATSUO (JP)
MOMOTAKE ATSUYA (JP)
FUKUSHIMA SYUN (JP)
Application Number:
PCT/JP2014/063754
Publication Date:
November 27, 2014
Filing Date:
May 23, 2014
Export Citation:
Assignee:
UNIV KEIO (JP)
UNIV TSUKUBA (JP)
UNIV TSUKUBA (JP)
International Classes:
C09B44/12; C09B67/20; C12Q1/04; G01N21/64; C09B29/036; C09B29/08
Domestic Patent References:
| WO2010034623A1 | 2010-04-01 |
Foreign References:
| JP2012137549A | 2012-07-19 | |||
| JP2005029726A | 2005-02-03 | |||
| JPS6470452A | 1989-03-15 | |||
| JP2001316231A | 2001-11-13 | |||
| JPH08122326A | 1996-05-17 | |||
| JPH095243A | 1997-01-10 | |||
| JPH11508355A | 1999-07-21 | |||
| JP2004212132A | 2004-07-29 | |||
| JP2012014066A | 2012-01-19 |
Other References:
MUTSUO NURIYA: "Imaging Membrane Potential Dynamics in Neurons", THE REVIEW OF LASER ENGINEERING, vol. 40, no. 4, 2012, pages 224 - 229, XP055075671
GAO,L.H. ET AL.: "Second-Order Nonlinear Optical Langmuir-Blodgett Films Based on a Series of Azo Rare-Earth Coordination Compounds", CHEMISTRY OF MATERIALS, vol. 7, no. 6, 1995, pages 1047 - 1049, XP055295881
See also references of EP 3000848A4
GAO,L.H. ET AL.: "Second-Order Nonlinear Optical Langmuir-Blodgett Films Based on a Series of Azo Rare-Earth Coordination Compounds", CHEMISTRY OF MATERIALS, vol. 7, no. 6, 1995, pages 1047 - 1049, XP055295881
See also references of EP 3000848A4
Attorney, Agent or Firm:
SHOBAYASHI, Masayuki et al. (JP)
Right wood Masayuki (JP)
Right wood Masayuki (JP)
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