Title:
COMPOUND HAVING EV71 AND/OR CVA16 VIRUS INHIBITORY ACTIVITY AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/027457
Kind Code:
A1
Abstract:
A compound which has EV71 and/or CVA16 virus inhibitory activity and an application thereof, belonging to the field of antiviral drugs. The compound has the structure of formula (I), has good EV71 and/or CVA16 virus replication inhibitory activity, can effectively inhibit the replication and protein expression of EV71 and/or CVA16 viruses in host cells, and has the potential to be used as an anti-EV71 and/or CVA16 virus drug for the prevention and/or treatment of diseases and/or conditions caused by EV71 and/or CVA16 viruses.
Inventors:
HE SUDAN (CN)
ZHANG XIAOHU (CN)
HU ZHILIN (CN)
WANG XINHUI (CN)
ZHANG XIAOHU (CN)
HU ZHILIN (CN)
WANG XINHUI (CN)
Application Number:
PCT/CN2023/106356
Publication Date:
February 08, 2024
Filing Date:
July 07, 2023
Export Citation:
Assignee:
SUZHOU INST OF SYSTEMS MEDICINE (CN)
UNIV SOOCHOW (CN)
UNIV SOOCHOW (CN)
International Classes:
A61K31/506; C07D401/12; A61P31/14; C07D495/04
Domestic Patent References:
| WO2010119050A1 | 2010-10-21 |
Foreign References:
| CN116120282A | 2023-05-16 | |||
| CN104744433A | 2015-07-01 | |||
| US20090012107A1 | 2009-01-08 | |||
| CN102066339A | 2011-05-18 | |||
| US20140323418A1 | 2014-10-30 |
Other References:
DATABASE REGISTRY 4 February 2014 (2014-02-04), ANONYMOUS: "2,4-Pyrimidinediamine, 5-chloro-N2-methyl-N4-6-quinolinyl- (CA INDEX NAME)", XP093136304, retrieved from STNext Database accession no. 1536927-21-5
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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