Title:
COMPOUND HAVING NOVEL STRUCTURE, ANTI-INFLAMMATORY AGENT COMPRISING SAME, AND CYCLOOXYGENASE-2 INHIBITOR COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2019/182395
Kind Code:
A1
Abstract:
In the compound of the present invention and in an anti-inflammatory agent, a cyclooxygenase-2 inhibitor, a therapeutic agent for brain diseases, and an MRI contrast medium, which each comprise the same compound, the compound of the present invention has the structure represented by chemical formula 1 according to the present invention.
Inventors:
CHANG YONG MIN (KR)
KIM HEE KYEONG (KR)
KIM HEE KYEONG (KR)
Application Number:
PCT/KR2019/003353
Publication Date:
September 26, 2019
Filing Date:
March 22, 2019
Export Citation:
Assignee:
CHANG YONG MIN (KR)
International Classes:
C07D257/02; A61K49/10; A61P29/00
Foreign References:
| US20050002859A1 | 2005-01-06 | |||
| US20100111858A1 | 2010-05-06 |
Other References:
SUNG B KYUNG : "Gadolinium-complexes of DO3A conjugates as inflammation targeted magnetic resonance imaging contrast agents", THESIS FOR THE DEGREE OF MASTER OF SCIENCE, 31 January 2018 (2018-01-31), Korea, pages 1 - 37, XP009523622
KIM, H.-K.: "Gd3+-based MRI contrast agents as potential inflammation targeting", THE 5TH INTERNATIONAL CONFERENCE ON MRI (ICMRI2017) AND 22ND ANNUAL SCIENTIFIC MEETING OF KSMRM, 23 March 2017 (2017-03-23), pages 106, XP009523655
JASHIM UDDIN , BRENDA C KEBREAB GHEBRESELASIE , LAWRENCE J MMARNETT : "Design, synthesis, and structure-activity relationship studies of fluorescent inhibitors of cycloxygenase-2 as targeted optical imaging agents", BIOCONJUGATE CHEMISTRY, vol. 24, no. 4, 15 March 2013 (2013-03-15), pages 712 - 723, XP055138177, ISSN: 1043-1802, DOI: 10.1021/bc300693w
KIM, H.-K.: "Gd3+-based MRI contrast agents as potential inflammation targeting", THE 5TH INTERNATIONAL CONFERENCE ON MRI (ICMRI2017) AND 22ND ANNUAL SCIENTIFIC MEETING OF KSMRM, 23 March 2017 (2017-03-23), pages 106, XP009523655
JASHIM UDDIN , BRENDA C KEBREAB GHEBRESELASIE , LAWRENCE J MMARNETT : "Design, synthesis, and structure-activity relationship studies of fluorescent inhibitors of cycloxygenase-2 as targeted optical imaging agents", BIOCONJUGATE CHEMISTRY, vol. 24, no. 4, 15 March 2013 (2013-03-15), pages 712 - 723, XP055138177, ISSN: 1043-1802, DOI: 10.1021/bc300693w
Attorney, Agent or Firm:
NAM, Gun Pil et al. (KR)
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