A COMPOUND FOR INHIBITING 11β-HYDROXY STEROID DEHYDROGENASE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

WIPO Patent Application WO/2013/019091

A3

Disclosed are a novel compound or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition including the same for inhibiting human 11-β-hydroxy steroid dehydrogenase type 1 (11β-HSD1).　The disclosed compound and the pharmaceutical composition including the same for inhibiting human 11-β-hydroxy steroid dehydrogenase type 1 (11β-HSD1) are excellent in activity and solubility, and is more efficient in formulation and transfer.

LEE INHEE (KR)
PYEON DOOHYEOK (KR)
SHIN MYOUNGHYEON (KR)
HWANG JEONGUN (KR)
PARK CHANGMIN (KR)
KIM SEHOAN (KR)
CHAE HEEIL (KR)
MOON SOONYOUNG (KR)
KIM SOYOUN (KR)
RHEE JAEKEOL (KR)

PCT/KR2012/006216

April 25, 2013

August 06, 2012

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HYUNDAI PHARM CO LTD (KR)
LEE INHEE (KR)
PYEON DOOHYEOK (KR)
SHIN MYOUNGHYEON (KR)
HWANG JEONGUN (KR)
PARK CHANGMIN (KR)
KIM SEHOAN (KR)
CHAE HEEIL (KR)
MOON SOONYOUNG (KR)
KIM SOYOUN (KR)
RHEE JAEKEOL (KR)

C07C311/05; A61K31/18; A61P3/10; A61P9/12; C07C233/00

WO2007057768A2

2007-05-24

KR20120111347A	2012-10-10
US7842707B2	2010-11-30

KIM, SE HOAN ET AL.: "Synthesis and Biological Evaluation of Cyclic Sulfamide Derivatives as llbeta-Hydroxysteroid Dehydrogenase 1 Inhibitors", ACS MEDICINAL CHEMISTRY LETTERS, vol. 3, 17 January 2012 (2012-01-17), pages 88 - 93

KIM, Moon Jae et al. (41-3 Seosomun-dong,Jung-Gu, Seoul 100-813, KR)

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