Title:
COMPOUND FOR PREPARING MYOCARDIAL CELLS AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/041645
Kind Code:
A1
Abstract:
The present invention relates to the field of biomedicine, in particular to the field of regenerative medicine. Specifically, the present invention relates to a compound for preparing myocardial cells and use thereof, and a method for differentiating pluripotent stem cells, such as induced pluripotent stem cells, into myocardial cells by using the compound.
Inventors:
ZHAO YANG (CN)
YANG XIAOCHUN (CN)
CEN ZIMU (CN)
YANG XIAOCHUN (CN)
CEN ZIMU (CN)
Application Number:
PCT/CN2023/115013
Publication Date:
February 29, 2024
Filing Date:
August 25, 2023
Export Citation:
Assignee:
UNIV BEIJING (CN)
International Classes:
C12N5/0735; C12N5/077; C12N5/10
Foreign References:
| CN113337458A | 2021-09-03 | |||
| US20200216812A1 | 2020-07-09 | |||
| CN106987555A | 2017-07-28 | |||
| CN108359636A | 2018-08-03 | |||
| CN108060125A | 2018-05-22 |
Other References:
BALAFKAN, N. ET AL.: "A Method for Differentiating Human Induced Pluripotent Stem Cells toward Functional Cardiomyocytes in 96-well Microplates", SCIENTIFIC REPORTS, vol. 10, 28 October 2020 (2020-10-28), XP093100889, DOI: 10.1038/s41598-020-73656-2
YANG XIAOCHUN, CHEN DAICHAO, SUN QIUSHI, WANG YAO, XIA YU, YANG JINYU, LIN CHANG, DANG XIN, CEN ZIMU, LIANG DONGDONG, WEI RONG, XU: "A live-cell image-based machine learning strategy for reducing variability in PSC differentiation systems", CELL DISCOVERY, NATURE PUBLISHING GROUP, GB, vol. 9, no. 1, 6 June 2023 (2023-06-06), GB , pages 53, XP093142146, ISSN: 2056-5968, DOI: 10.1038/s41421-023-00543-1
YANG XIAOCHUN, CHEN DAICHAO, SUN QIUSHI, WANG YAO, XIA YU, YANG JINYU, LIN CHANG, DANG XIN, CEN ZIMU, LIANG DONGDONG, WEI RONG, XU: "A live-cell image-based machine learning strategy for reducing variability in PSC differentiation systems", CELL DISCOVERY, NATURE PUBLISHING GROUP, GB, vol. 9, no. 1, 6 June 2023 (2023-06-06), GB , pages 53, XP093142146, ISSN: 2056-5968, DOI: 10.1038/s41421-023-00543-1
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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