Title:
COMPOUND FOR RNA CAPPING AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/051696
Kind Code:
A1
Abstract:
The present invention relates to a compound for RNA capping and use thereof and belongs to the technical field of genetic engineering. The compound has a structure represented by formula I. The compound is used for capping an mRNA5' end, and the capping efficiency is good. The capped mRNA can stably express a protein with a high yield. By using the compound of the present invention as a cap structure to prepare an RNA vaccine or an RNA medicament, the cost can be greatly reduced. The compound of the present invention has wide application prospects in preparing RNA vaccines or RNA medicaments.
Inventors:
ZHANG JIANCUN (CN)
ZHANG LIJUN (CN)
ZHOU YIQIAN (CN)
CHEN JIAFENG (CN)
ZHANG JUFU (CN)
LI SUYONG (CN)
LIU YANHUI (CN)
GUO CHEN (CN)
TANG WANJUN (CN)
WU FENG (CN)
HE XIAOXI (CN)
GUO QI (CN)
CHEN HUIXUAN (CN)
WANG KUN (CN)
LI DEYAO (CN)
ZHANG LIJUN (CN)
ZHOU YIQIAN (CN)
CHEN JIAFENG (CN)
ZHANG JUFU (CN)
LI SUYONG (CN)
LIU YANHUI (CN)
GUO CHEN (CN)
TANG WANJUN (CN)
WU FENG (CN)
HE XIAOXI (CN)
GUO QI (CN)
CHEN HUIXUAN (CN)
WANG KUN (CN)
LI DEYAO (CN)
Application Number:
PCT/CN2023/117043
Publication Date:
March 14, 2024
Filing Date:
September 05, 2023
Export Citation:
Assignee:
GUANGZHOU HENOVCOM BIOSCIENCE CO LTD (CN)
International Classes:
C07H19/20; A61K31/7125; C07H1/00; C12N15/10; C12P19/34
Domestic Patent References:
| WO2022051677A1 | 2022-03-10 | |||
| WO2023033551A1 | 2023-03-09 |
Foreign References:
| CN114941018A | 2022-08-26 | |||
| CN113603739A | 2021-11-05 | |||
| CN111944864A | 2020-11-17 | |||
| CN108366604A | 2018-08-03 | |||
| CN113957108A | 2022-01-21 | |||
| CN115260264A | 2022-11-01 |
Attorney, Agent or Firm:
GUANGZHOU HAIXIN UNION PATENT LAW OFFICE (CN)
Download PDF:
Previous Patent: HIGH-THRUST PIEZOELECTRIC DRIVE DEVICE
Next Patent: IMAGE FUSION METHOD AND APPARATUS, ELECTRONIC DEVICE, AND STORAGE MEDIUM
Next Patent: IMAGE FUSION METHOD AND APPARATUS, ELECTRONIC DEVICE, AND STORAGE MEDIUM