Title:
COMPOUND SERVING AS CATIONIC LIPID
Document Type and Number:
WIPO Patent Application WO/2018/225871
Kind Code:
A1
Abstract:
The present invention provides a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. (In the formula, R1 represents a hydrogen atom or a hydroxymethyl group; n1 represents 1 or 2; A1 and A2 may be the same or different, and each represents a linear C9-C20 alkylene group or the like; M1 and M2 may be the same or different, and each represents -OC(O)-, -C(O)O- or -NHC(O)-; B1 and B2 may be the same or different, and each represents a linear or branched C1-C12 alkyl group or the like; R2 is absent or represents a C1-C3 alkyl group; and in cases where R2 is absent, Y is also absent, while in cases where R2 is a C1-C3 alkyl group, Y is a pharmaceutically acceptable anion.)
Inventors:
NAOI TOMOYUKI (JP)
HOSOE SHINTARO (JP)
UEMURA YASUNORI (JP)
YAGI KAORI (JP)
HOSOE SHINTARO (JP)
UEMURA YASUNORI (JP)
YAGI KAORI (JP)
Application Number:
PCT/JP2018/022220
Publication Date:
December 13, 2018
Filing Date:
June 11, 2018
Export Citation:
Assignee:
KYOWA HAKKO KIRIN CO LTD (JP)
International Classes:
C07C219/08; A61K31/7088; A61K35/00; A61K47/18; A61P1/00; A61P1/16; A61P11/00; A61P35/00; C07C229/16; C07C229/30; C07C237/06; C12N15/113
Domestic Patent References:
| WO2017049245A2 | 2017-03-23 |
Foreign References:
| US20170119904A1 | 2017-05-04 |
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
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