Title:
COMPOUND USED AS INHIBITOR OF CDK4 KINASE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/051702
Kind Code:
A1
Abstract:
The present invention relates to a compound used as an inhibitor of a CDK4 kinase and use thereof. Specifically, the compound of the present invention has a structure represented by formula (I), wherein the definitions of each group and each substituent group are as described in the specification. The compound of the present invention can be used as an inhibitor of a cyclin-dependent kinase (CDK), is used for treating or preventing proliferative diseases (such as cancer), and is in particular used for modulating and treating related diseases caused by the abnormal activity of the cyclin-dependent kinase (CDK).
Inventors:
LIANG APENG (CN)
WANG KAI (CN)
CHEN SHAOQING (CN)
LI JUN (CN)
WU YUSHENG (CN)
LI MEIHUA (CN)
YIN ZHOU (CN)
LONG YI (CN)
NIU CHENGSHAN (CN)
WANG KAI (CN)
CHEN SHAOQING (CN)
LI JUN (CN)
WU YUSHENG (CN)
LI MEIHUA (CN)
YIN ZHOU (CN)
LONG YI (CN)
NIU CHENGSHAN (CN)
Application Number:
PCT/CN2023/117094
Publication Date:
March 14, 2024
Filing Date:
September 05, 2023
Export Citation:
Assignee:
TYK MEDICINES INC (CN)
International Classes:
C07D413/14; A61K31/506; A61K31/519; A61K31/52; A61K31/527; A61K31/5355; A61K31/538; A61K31/542; A61P3/00; A61P9/00; A61P29/00; A61P31/00; A61P35/00; A61P37/00; C07D401/14; C07D403/10; C07D405/12; C07D405/14; C07D413/10; C07D473/34; C07D487/04; C07D513/04
Domestic Patent References:
| WO2023205892A1 | 2023-11-02 | |||
| WO2023196517A1 | 2023-10-12 | |||
| WO2021030623A1 | 2021-02-18 | |||
| WO2020224568A1 | 2020-11-12 | |||
| WO2012066065A1 | 2012-05-24 | |||
| WO2004041810A1 | 2004-05-21 | |||
| WO2018045957A1 | 2018-03-15 |
Foreign References:
| CN116947840A | 2023-10-27 | |||
| CN112313219A | 2021-02-02 | |||
| CN107286134A | 2017-10-24 | |||
| CN105916848A | 2016-08-31 | |||
| CN113382991A | 2021-09-10 | |||
| CN112334451A | 2021-02-05 |
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
Download PDF:
Previous Patent: SCHEDULING OPTIMIZATION METHOD AND APPARATUS, DEVICE, AND STORAGE MEDIUM
Next Patent: SEED CRYSTAL HOLDER AND CRYSTAL GROWTH METHOD
Next Patent: SEED CRYSTAL HOLDER AND CRYSTAL GROWTH METHOD