COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILISATION

Title:

COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILISATION

Document Type and Number:

WIPO Patent Application WO/2012/054535

Kind Code:

A3

Abstract:

The invention relates to classes of pharmaceutically-active heterocyclic compounds and pharmaceutically acceptable salts, and hydrates thereof, and compositions comprising the same. The invention also relates to methods for treating or preventing a disease or disorder, which comprises administering a therapeutically or prophylactically effective amount a compound described herein.

Inventors:

ONICIU DANIELA CARMEN (FR)
DASSEUX JEAN-LOUIS HENRI (FR)
BARBARAS RONALD (FR)
KOCHUBEY VALERY (RU)
KOVALSKY DMITRY (RU)
RODIN OLEG GENNADIEVICH (RU)
GEOFFROY OTTO (US)
RZEPIELA ANNA (NL)

Application Number:

PCT/US2011/056780

Publication Date:

July 26, 2012

Filing Date:

October 18, 2011

Export Citation:

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Assignee:

CERENIS THERAPEUTICS HOLDING SA (FR)
ONICIU DANIELA CARMEN (FR)
DASSEUX JEAN-LOUIS HENRI (FR)
BARBARAS RONALD (FR)
KOCHUBEY VALERY (RU)
KOVALSKY DMITRY (RU)
RODIN OLEG GENNADIEVICH (RU)
GEOFFROY OTTO (US)
RZEPIELA ANNA (NL)

International Classes:

A61K31/505; A61K31/44

Domestic Patent References:

WO2005076007A2	2005-08-18
WO2012054535A2	2012-04-26

Foreign References:

US5288726A	1994-02-22
US5763448A	1998-06-09
US3935222A	1976-01-27
US6632814B1	2003-10-14
US20070249555A1	2007-10-25
US3939159A	1976-02-17

Other References:

ZHAN C. ET AL.: "Molecular modeling of purinergic receptor P2Y12 and interaction with its antagonists", JOURNAL OF MOLECULAR GRAPHIES AND MODELLING, vol. 26, no. 1, 2007, pages 20 - 31, XP022132983

Attorney, Agent or Firm:

LANGER, Matthew E. et al. (777 6th Street NW,Suite 110, Washington District of Columbia, US)

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