Title:
COMPOUNDS HAVING SUBSTITUTED 4-MEMBERS RING STRUCTURE AND THEIR MEDICINE USES
Document Type and Number:
WIPO Patent Application WO/2008/067711
Kind Code:
A1
Abstract:
Disclosed are compounds having substituted 4-members ring structure represented by
general formula I or general formula II, or pharmaceutically acceptable salts, esters,
solvates, metal complexes thereof, or prodrugs having same pharmacological action.
And disclosed is the use as a kind of glucagons-1 acceptor regulators for preventing
and/or treating metabolic disorder disease (including but not limited by diabetes,
insuline resistance and adiposis), angiocardiopathy and nerve regression
diseases (such as Alzheimer's disease).
Inventors:
WANG MINGWEI (CN)
CHEN DESU (CN)
LI NA (CN)
LIU QING (CN)
LIAO JIAYU (CN)
CHEN DESU (CN)
LI NA (CN)
LIU QING (CN)
LIAO JIAYU (CN)
Application Number:
PCT/CN2007/002959
Publication Date:
June 12, 2008
Filing Date:
October 16, 2007
Export Citation:
Assignee:
SHANGHAI INST MATERIA MEDICA (CN)
WANG MINGWEI (CN)
CHEN DESU (CN)
LI NA (CN)
LIU QING (CN)
LIAO JIAYU (CN)
WANG MINGWEI (CN)
CHEN DESU (CN)
LI NA (CN)
LIU QING (CN)
LIAO JIAYU (CN)
International Classes:
C07D333/40; A61K31/381; A61P3/00; A61P3/04; A61P3/10; A61P9/00; A61P25/00; A61P25/16
Foreign References:
| CN1884278A | 2006-12-27 | |||
| CN1626521A | 2005-06-15 |
Attorney, Agent or Firm:
KINGSOUND & PARTNERS (Block B KingSound International Center, 116 Zizhuyuan Road, Haidian District, Beijing 7, CN)
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