Title:
COMPOUNDS AND METHODS FOR INDUCING MESENCHYMAL STEM CELLS INTO CHONDROCYTES
Document Type and Number:
WIPO Patent Application WO/2016/112513
Kind Code:
A1
Abstract:
This invention provides compounds and compositions for inducing mesenchymal stem cells into chondrocytes ex vivo and in vivo. The compound could lead to a stem cell-based therapy for osteoarthritis and joint injuries. The present invention also provides the preparation method of the compounds of the present invention, the use of the compound and the method to treat osteoarthritis and joint injuries.
Inventors:
JIANG BAISHAN (CN)
DING SHENG (CN)
HU LANGXI (CN)
LI XIANGNAN (CN)
HE CHUANG (CN)
DING SHENG (CN)
HU LANGXI (CN)
LI XIANGNAN (CN)
HE CHUANG (CN)
Application Number:
PCT/CN2015/070787
Publication Date:
July 21, 2016
Filing Date:
January 15, 2015
Export Citation:
Assignee:
GUANGZHOU INST BIOMED & HEALTH (CN)
International Classes:
C07D277/06; A61K31/427; A61P19/02; C07D237/10; C07D265/00
Domestic Patent References:
| WO2012129562A2 | 2012-09-27 |
Other References:
DATABASE REGISTRY 13 August 2008 (2008-08-13), retrieved from STN Database accession no. 1040648-55-2;
DATABASE REGISTRY 13 August 2008 (2008-08-13), retrieved from STN Database accession no. 1040666-38-3;
DATABASE REGISTRY 28 December 2008 (2008-12-28), retrieved from STN Database accession no. 1091081-46-7;
DATABASE REGISTRY 28 December 2008 (2008-12-28), retrieved from STN Database accession no. 1091063-10-3;
DATABASE REGISTRY 29 December 2008 (2008-12-29), retrieved from STN Database accession no. 1091167-65-5;
DATABASE REGISTRY 29 December 2008 (2008-12-29), retrieved from STN Database accession no. 1091167-73-5;
DATABASE REGISTRY 13 August 2008 (2008-08-13), retrieved from STN Database accession no. 1040666-38-3;
DATABASE REGISTRY 28 December 2008 (2008-12-28), retrieved from STN Database accession no. 1091081-46-7;
DATABASE REGISTRY 28 December 2008 (2008-12-28), retrieved from STN Database accession no. 1091063-10-3;
DATABASE REGISTRY 29 December 2008 (2008-12-29), retrieved from STN Database accession no. 1091167-65-5;
DATABASE REGISTRY 29 December 2008 (2008-12-29), retrieved from STN Database accession no. 1091167-73-5;
Attorney, Agent or Firm:
BOSS & YOUNG PATENT AND TRADEMARK LAW OFFICE (Tower A Bldg. No. 1, GT International Center,,Jia 3 Yongandongli, Jianguomenwai Avenue, Chaoyang District, Beijing 2, CN)
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