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Title:
COMPOUNDS AND METHODS FOR THE INHIBITION OF THE EXPRESSION OF VCAM-1
Document Type and Number:
WIPO Patent Application WO1998051662
Kind Code:
A3
Abstract:
This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases.

Inventors:
SOMERS PATRICIA K
HOONG LEE K
MENG CHARLES Q
Application Number:
PCT/US1998/009781
Publication Date:
March 02, 2000
Filing Date:
May 14, 1998
Export Citation:
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Assignee:
ATHEROGENICS INC (US)
International Classes:
A01N37/02; A61K31/095; A61K31/10; A61K31/133; A61K31/18; A61K31/19; A61K31/22; A61K31/222; A61K31/225; A61K31/336; A61K31/341; A61K31/41; A61K31/7034; A61P9/10; A61P11/06; A61P17/00; A61P9/00; A61P17/06; A61P19/02; A61P21/02; A61P29/00; A61P43/00; C07C323/00; C07C323/18; C07C323/20; C07C323/21; C07C323/22; C07C323/25; C07C323/31; C07C323/56; C07C323/62; C07C323/66; C07C323/67; C07D257/04; C07D303/22; C07D307/52; C07D307/68; C07H15/203; (IPC1-7): C07C323/56; C07C323/20; C07D307/68; C07C323/67; C07C317/22; C07C323/66; C07D307/52; C07C323/25; C07D307/70; C07D303/22; C07D303/28; C07D257/04; A61K31/19; A61K31/10; A61K31/34; A61K31/225
Domestic Patent References:
WO1995030415A11995-11-16
WO1996012703A11996-05-02
WO1998022418A11998-05-28
Foreign References:
EP0348203A11989-12-27
EP0317165A11989-05-24
EP0621255A11994-10-26
EP0405788A21991-01-02
EP0190682A21986-08-13
DE2716125A11977-10-27
US4755524A1988-07-05
US4115590A1978-09-19
US3179701A1965-04-20
GB1136539A1968-12-11
GB1148550A1969-04-16
GB1199871A1970-07-22
EP0292660A21988-11-30
US5262439A1993-11-16
Other References:
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002115597
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002115598
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002115599
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002115600
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002115601
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002115602
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002115603
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002115604
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002115683
L. COMINACINI ET AL, FREE RADICAL BIOLOGY AND MEDICINE, vol. 22, no. 1-2, 1996, pages 117 - 127, XP002095164
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002124423
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002124424
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