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Patent Searching and Data


Title:
COMPOUNDS AND METHODS FOR MODULATING ANGIOTENSINOGEN EXPRESSION
Document Type and Number:
WIPO Patent Application WO/2017/062816
Kind Code:
A8
Abstract:
Disclosed herein are compositions and compounds comprising modified oligonucleotides for modulating AGT and modulating a RAAS pathway related disease, disorder and/or condition in an individual in need thereof. A RAAS pathway related disease, disorder and/or condition in an individual such as hypertension can be treated, ameliorated, delayed or prevented with the administration of antisense compounds targeted to AGT.

Inventors:
MULLICK, Adam (2855 Gazelle Ct, Carlsbad, CA, 92010, US)
GRAHAM, Mark, J. (2855 Gazelle Ct, Carlsbad, CA, 92010, US)
SETH, Punit, P. (2855 Gazelle Ct, Carlsbad, CA, 92010, US)
FREIER, Susan, M. (2855 Gazelle Ct, Carlsbad, CA, 92010, US)
Application Number:
US2016/056068
Publication Date:
April 13, 2017
Filing Date:
October 07, 2016
Export Citation:
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Assignee:
IONIS PHARMACEUTICALS, INC. (2855 Gazelle Court, Carlsbad, CA, 92010, US)
International Classes:
A61K31/7088; A61K9/00; A61K31/7125; C07H21/02
Attorney, Agent or Firm:
GINGRICH, Brenden et al. (Knobbe Martens LLP, 2040 Main Street 14th Floo, Irvine CA, 92614, US)
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