Title:
COMPOUNDS THAT INHIBIT 3C AND 3CL PROTEASES AND METHODS OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/042343
Kind Code:
A3
Abstract:
Compounds, specifically protease inhibitors, more specifically 3C and 3CL protease inhibitors, for the treatment of viral infections, and methods of preparing and using such compounds.
Inventors:
BOTYANSZKI JANOS (US)
CATALANO JOHN G (US)
CHONG PEK YOKE (US)
DICKSON HAMILTON (US)
JIN QI (US)
LEIVERS ANNA (US)
MAYNARD ANDREW (US)
LIAO XIANGMIN (US)
MILLER JOHN (US)
SHOTWELL JOHN BRAD (US)
TAI VINCENT WING-FAI (US)
THALJI REEMA (US)
CATALANO JOHN G (US)
CHONG PEK YOKE (US)
DICKSON HAMILTON (US)
JIN QI (US)
LEIVERS ANNA (US)
MAYNARD ANDREW (US)
LIAO XIANGMIN (US)
MILLER JOHN (US)
SHOTWELL JOHN BRAD (US)
TAI VINCENT WING-FAI (US)
THALJI REEMA (US)
Application Number:
PCT/IB2017/055206
Publication Date:
April 19, 2018
Filing Date:
August 30, 2017
Export Citation:
Assignee:
GLAXOSMITHKLINE IP NO 2 LTD (GB)
International Classes:
C07D403/12; A61K31/4155; A61P31/00; C07D207/27; C07D401/12; C07D413/12; C07D417/12
Domestic Patent References:
| WO2013049382A2 | 2013-04-04 | |||
| WO2006061714A2 | 2006-06-15 |
Other References:
PRIOR ALLAN M ET AL: "Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 23, no. 23, 30 September 2013 (2013-09-30), pages 6317 - 6320, XP028760181, ISSN: 0960-894X, DOI: 10.1016/J.BMCL.2013.09.070
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