Title:
COMPOUNDS FOR TREATING CERTAIN LEUKEMIAS
Document Type and Number:
WIPO Patent Application WO/2020/061086
Kind Code:
A3
Abstract:
Provided herein are compounds, preferably compounds inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, compositions thereof, and methods of their preparation, and methods of inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, and methods for treating diseases wherein modulation of BCR-ABL1 activity prevents, inhibits, or ameliorates the pathology and/or symptomology of the disease.
Inventors:
ROMERO F ANTHONY (US)
KIRSCHBERG THORSTEN A (US)
HALCOMB RANDALL (US)
XU YINGZI (US)
KIRSCHBERG THORSTEN A (US)
HALCOMB RANDALL (US)
XU YINGZI (US)
Application Number:
PCT/US2019/051567
Publication Date:
July 23, 2020
Filing Date:
September 17, 2019
Export Citation:
Assignee:
TERNS INC (US)
International Classes:
A61K31/4184; A61K31/4164; C07D235/04; C07D235/08
Foreign References:
| US20050197375A1 | 2005-09-08 | |||
| US20020010343A1 | 2002-01-24 | |||
| US20110046133A1 | 2011-02-24 |
Attorney, Agent or Firm:
KUZELKA, Jane et al. (US)
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