COMPOUNDS - GLAXOSMITHKLINE IP DEV LTD

Title:

COMPOUNDS

Document Type and Number:

WIPO Patent Application WO/2016/011930

Kind Code:

A1

Abstract:

The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example Alzheimer's disease.

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Inventors:

WAN ZEHONG (CN)
ZHANG XIAOMIN (CN)
WANG JIAN (CN)
SENDER MATTHEW ROBERT (US)
MANAS ERIC STEVEN (US)
RIVERO RAPHAEL ANTHONY (US)
PERO JOSEPH E (US)
NEIPP CHRISTOPHER ERNST (US)
PATEL VIPULKUMAR KANTIBHAI (GB)

Application Number:

PCT/CN2015/084606

Publication Date:

January 28, 2016

Filing Date:

July 21, 2015

Export Citation:

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Assignee:

GLAXOSMITHKLINE IP DEV LTD (GB)
GLAXOSMITHKLINE CHINA R&D COMPANY LTD (CN)

International Classes:

C07D487/14; A61K31/519; A61K31/527; A61P9/10; A61P25/28; C07D487/20; C07D491/20; C07D513/12

Domestic Patent References:

WO2014114694A1

2014-07-31

Other References: