Title:
COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2017/012576
Kind Code:
A1
Abstract:
Disclosed are novel compounds that inhibit LRRK2 kinase activity, processes for their preparation, compositions containing them and their use in the treatment of or prevention of diseases characterized by LRRK2 kinase activity, for example Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis(ALS).
Inventors:
DING XIAO (CN)
JIN YUN (CN)
LIU QIAN (CN)
REN FENG (CN)
SANG YINGXIA (CN)
STASI LUIGI PIERO (CN)
WAN ZEHONG (CN)
WANG HAILONG (CN)
XING WEIQIANG (CN)
ZHAN YANG (CN)
ZHAO BAOWEI (CN)
JIN YUN (CN)
LIU QIAN (CN)
REN FENG (CN)
SANG YINGXIA (CN)
STASI LUIGI PIERO (CN)
WAN ZEHONG (CN)
WANG HAILONG (CN)
XING WEIQIANG (CN)
ZHAN YANG (CN)
ZHAO BAOWEI (CN)
Application Number:
PCT/CN2016/090962
Publication Date:
January 26, 2017
Filing Date:
July 22, 2016
Export Citation:
Assignee:
GLAXOSMITHKLINE IP DEV LTD (GB)
GLAXOSMITHKLINE (CHINA) R & D COMPANY LTD (CN)
GLAXOSMITHKLINE (CHINA) R & D COMPANY LTD (CN)
International Classes:
C07D231/56; A61K31/416; A61P25/16
Domestic Patent References:
| WO2006047516A2 | 2006-05-04 | |||
| WO2012009258A2 | 2012-01-19 | |||
| WO2011106168A1 | 2011-09-01 | |||
| WO2015099196A1 | 2015-07-02 |
Foreign References:
| US20110130384A1 | 2011-06-02 |
Other References:
See also references of EP 3325449A4
Attorney, Agent or Firm:
KING & WOOD MALLESONS (CN)
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