Title:
COMPUTATIONAL SELECTION OF PROBES FOR LOCALIZING CHROMOSOME BREAKPOINTS
Document Type and Number:
WIPO Patent Application WO2005094291
Kind Code:
A3
Abstract:
The present invention provides a novel method for selecting genomic hybridization probes. The method generally includes the step of selecting a genomic interval of interest, identifying at least one potential hybridization probe that has known coordinates within the interval of interest, applying a numerical method to sample the identified probe(s) based on its genome coordinates, and selecting a probe based on the result of the numerical method.
Inventors:
KNOLL JOAN H M (US)
ROGAN PETER K (US)
ROGAN PETER K (US)
Application Number:
PCT/US2005/010290
Publication Date:
September 14, 2006
Filing Date:
March 28, 2005
Export Citation:
Assignee:
CHILDRENS MERCY HOSPITAL (US)
KNOLL JOAN H M (US)
ROGAN PETER K (US)
KNOLL JOAN H M (US)
ROGAN PETER K (US)
International Classes:
G01N33/48; C12Q1/68
Foreign References:
| US20040048253A1 | 2004-03-11 | |||
| US20040175743A1 | 2004-09-09 |
Other References:
DATABASE GENBANK [online] 3 December 2001 (2001-12-03), GARNER: "Wellcome Trust Sanger Institute", XP003013511, accession no. NCBI Database accession no. (AL161733)
DATABASE GENBANK [online] 17 March 2001 (2001-03-17), LLOYD, XP003013512, accession no. NCBI Database accession no. (AL359092)
See also references of EP 1740940A4
DATABASE GENBANK [online] 17 March 2001 (2001-03-17), LLOYD, XP003013512, accession no. NCBI Database accession no. (AL359092)
See also references of EP 1740940A4
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