COMPUTER-DIRECTED ASSEMBLY OF A POLYNUCLEOTIDE ENCODING A TARGET POLYPEPTIDE

Title:

COMPUTER-DIRECTED ASSEMBLY OF A POLYNUCLEOTIDE ENCODING A TARGET POLYPEPTIDE

Document Type and Number:

WIPO Patent Application WO2002081490

Kind Code:

A8

Abstract:

The present invention outlines a novel approach to utilizing the results of genomic sequence information by computer-directed polynucleotide assembly based upon information available in databases such as the human genome database. Specifically, the present invention may be used to select, synthesize and assemble a novel, synthetic target polynucleotide sequence encoding a target polypeptide. The target polynucleotide may encode a target polypeptide that exhibits enhanced or altered biological activity as compared to a model polypeptide encoded by a natural (wild-type) or model polynucleotide sequence.

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Inventors:

EVANS GLEN A (US)

Application Number:

PCT/US2002/001649

Publication Date:

May 21, 2004

Filing Date:

January 18, 2002

Export Citation:

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Assignee:

EGEA BIOSCIENCES INC (US)
EVANS GLEN A (US)

International Classes:

C12N15/09; C07H21/04; C07K1/00; C12N15/10; C12N15/66; C12P19/34; C12P21/02; C12Q1/68; G01N33/48; G01N33/50; G06F15/00; G16B30/20; C40B40/06; (IPC1-7): C12N15/10; C12N15/66; G06F15/00; G06F19/00

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