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Title:
CONDENSED PYRIMIDINE COMPOUND OR SALT THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/090719
Kind Code:
A1
Abstract:
Provided is a compound having an inhibitory effect on androgen receptors. A condensed pyrimidine compound represented by general formula (I) or a pharmacologically acceptable salt thereof (in the formula, X, Y, Z, R1, and R2 are as defined in the specification).

Inventors:
MINAMIGUCHI KAZUHISA (JP)
OKAJIMA SHIGEO (JP)
ASAI TAKAHIRO (JP)
ASAI MASANORI (JP)
OGINO YOSHIO (JP)
Application Number:
PCT/JP2016/084944
Publication Date:
June 01, 2017
Filing Date:
November 25, 2016
Export Citation:
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Assignee:
TAIHO PHARMACEUTICAL CO LTD (JP)
International Classes:
C07D471/04; A61K31/519; A61K31/55; A61P35/00; A61P43/00; C07D519/00
Domestic Patent References:
WO2015182712A12015-12-03
Foreign References:
JP2007517045A2007-06-28
JP2012500853A2012-01-12
JP2008526888A2008-07-24
JP2002088073A2002-03-27
Other References:
ZHANG, Y. ET AL.: "Discovery of a novel class anti-proliferative agents and potential inhibitors of EGFR tyrosine kinases based on 4- anilinotetrahydropyrido[4,3-d]pyrimidine scaffold: Design, synthesis and biological evaluations", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 23, no. 15, 6 June 2015 (2015-06-06), pages 4591 - 4607, XP055385185
TRUMP,R.P. ET AL.: "Design and Synthesis of an Array of Selective Androgen Receptor Modulators", JOURNAL OF COMBINATORIAL CHEMISTRY, vol. 9, no. 1, 2007, pages 107 - 114, XP008133518
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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