Title:
CONDENSED RING PYRIDINE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2012/014963
Kind Code:
A1
Abstract:
[Problem] To provide a compound which can act relying on an agonistic activity on cannabinoid receptor type 2 and is therefore useful as a novel and excellent prophylactic and/or therapeutic agent for diseases associated with cannabinoid receptor type 2.
[Solution] Examination was made on compounds having an agonistic activity on cannabinoid receptor type 2, and it is confirmed that a condensed ring pyridine compound of the invention has an excellent agonistic activity on cannabinoid receptor type 2. This condensed ring pyridine compound has an agonistic activity on cannabinoid receptor type 2, and can be used as a prophylactic and/or therapeutic agent for diseases associated with cannabinoid receptor type 2, such as inflammatory diseases and pain.
Inventors:
MATSUSHIMA YUJI (JP)
KAMEDA MINORU (JP)
HONDA SHUGO (JP)
SUGANO YUKIHITO (JP)
USUDA HIROYUKI (JP)
TERASAKA TADASHI (JP)
TERASAWA TAKESHI (JP)
NISHIGAKI FUSAKO (JP)
KAMEDA MINORU (JP)
HONDA SHUGO (JP)
SUGANO YUKIHITO (JP)
USUDA HIROYUKI (JP)
TERASAKA TADASHI (JP)
TERASAWA TAKESHI (JP)
NISHIGAKI FUSAKO (JP)
Application Number:
PCT/JP2011/067222
Publication Date:
February 02, 2012
Filing Date:
July 28, 2011
Export Citation:
Assignee:
ASTELLAS PHARMA INC (JP)
MATSUSHIMA YUJI (JP)
KAMEDA MINORU (JP)
HONDA SHUGO (JP)
SUGANO YUKIHITO (JP)
USUDA HIROYUKI (JP)
TERASAKA TADASHI (JP)
TERASAWA TAKESHI (JP)
NISHIGAKI FUSAKO (JP)
MATSUSHIMA YUJI (JP)
KAMEDA MINORU (JP)
HONDA SHUGO (JP)
SUGANO YUKIHITO (JP)
USUDA HIROYUKI (JP)
TERASAKA TADASHI (JP)
TERASAWA TAKESHI (JP)
NISHIGAKI FUSAKO (JP)
International Classes:
C07D217/26; A61K31/4725; A61K31/5377; A61K31/541; A61K31/553; A61P25/04; A61P29/00; A61P43/00; C07D237/34; C07D401/12; C07D405/12; C07D413/12; C07D495/04
Domestic Patent References:
| WO2008116816A1 | 2008-10-02 | |||
| WO2009015169A1 | 2009-01-29 | |||
| WO2009009550A1 | 2009-01-15 |
Foreign References:
| JP2008501758A | 2008-01-24 | |||
| JP2009504587A | 2009-02-05 | |||
| JP2008007493A | 2008-01-17 | |||
| JP2005539036A | 2005-12-22 | |||
| JP2006501228A | 2006-01-12 | |||
| JP2010509201A | 2010-03-25 | |||
| JP2009544755A | 2009-12-17 |
Other References:
SELLITTO I. ET AL.: "Novel sulfamoyl benzamides as selective CB2 agonists with improvwd in vitro metabolic stability", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 20, no. 1, January 2010 (2010-01-01), pages 387 - 391, XP026808850
See also references of EP 2599774A4
See also references of EP 2599774A4
Attorney, Agent or Firm:
MORITA, Hiroshi et al. (JP)
Morita 拓 (JP)
Morita 拓 (JP)
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Claims: