Title:
CONJUGATE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/140344
Kind Code:
A1
Abstract:
A technique is provided which enables simple and low-cost purification of biologically active proteins by means of a conjugate of a target substance capturing molecule and a protein which comprises the amino acid sequence in SEQ ID NO: 1, or a protein which comprises the amino acid sequence obtained by deleting, substituting or adding one or multiple amino acids in the amino acid sequence in SEQ ID NO: 1 and which has binding activity to a compound having -OH or -OR1 [R1 represents a hydrogen atom, an alkyl group or -PO3H2].
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Inventors:
IMAI KOHZOH (JP)
TSUJI SHOTARO (JP)
TSUJI SHOTARO (JP)
Application Number:
PCT/JP2016/056797
Publication Date:
September 09, 2016
Filing Date:
March 04, 2016
Export Citation:
Assignee:
UNIV TOKYO (JP)
KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION (JP)
KANAGAWA PREFECTURAL HOSPITAL ORGANIZATION (JP)
International Classes:
C12N15/09; A61K39/395; A61K45/00; A61K47/14; A61K47/42; A61K47/48; A61P3/00; A61P31/04; A61P31/12; A61P35/00; B01J20/24; C07K14/715; C07K16/00; C07K19/00; G01N33/53
Domestic Patent References:
| WO2013173501A2 | 2013-11-21 |
Foreign References:
| JP2004519663A | 2004-07-02 | |||
| JP2005503773A | 2005-02-10 | |||
| JPH11343300A | 1999-12-14 | |||
| JPH02226070A | 1990-09-07 | |||
| JP2003035708A | 2003-02-07 |
Other References:
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 26, 2001, pages 23456 - 23463, XP002477797
See also references of EP 3266870A4
See also references of EP 3266870A4
Attorney, Agent or Firm:
TANAI Sumio et al. (JP)
Sumio Tanai (JP)
Sumio Tanai (JP)
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