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Title:
CONJUGATES OF FERRITES AND OLIGONUCLEOTIDES, WHICH BOND SPECIFICALLY TO CERTAIN TARGET STRUCTURES
Document Type and Number:
WIPO Patent Application WO1996040273
Kind Code:
A3
Inventors:
PFEFFERER DETLEV
KRESSE MAYK
PLATZEK JOHANNES
NIEDBALLA ULRICH
GRIES HEINZ
RADUECHEL BERND
GOLD LARRY
Application Number:
EP9602442W
Publication Date:
March 27, 1997
Filing Date:
June 05, 1996
Export Citation:
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Assignee:
SCHERING AG (DE)
NEXSTAR PHARMACEUTICALS INC (DE)
International Classes:
C07H21/00; A61K31/70; A61K49/00; A61K49/18; A61K51/00; A61K51/12; C07F15/02; C07F19/00; (IPC1-7): A61K49/00; A61K51/04
Domestic Patent References:
WO1986005815A11986-10-09
WO1993023570A11993-11-25
WO1994001448A11994-01-20
WO1996002669A11996-02-01
Foreign References:
US5160725A1992-11-03
EP0295965A21988-12-21
EP0640350A21995-03-01
US5270163A1993-12-14
DE4424922A11996-01-18
US5516670A1996-05-14
Other References:
IVERSEN PL ET AL: "Binding of antisense phosphorothioate oligonucleotides to murine lymphocytes is lineage specific and inducible.", ANTISENSE RES DEV, FALL 1992, VOL. 2, NO. 3, PAGE(S) 223-33, XP000615946
PIRRUCCELLO SJ ET AL: "HIV-1 rev antisense phosphorothioate oligonucleotide binding to human mononuclear cells is cell type specific and inducible.", ANTISENSE RES DEV, WINTER 1994, VOL. 4, NO. 4, PAGE(S) 285-9, XP002024861
DEWANJEE MK ET AL: "Development of sensitive radioiodinated anti-sense oligonucleotide probes by conjugation technique.", BIOCONJUG CHEM, JUL-AUG 1991, VOL. 2, NO. 4, PAGE(S) 195-200, XP002024862
TAKAKURA Y. ET AL: "Control of in vivo characteristics of gene and antisense DNA disposition", JPN. J. CANCER CHEMOTHER., 1994, VOL. 21, NO. 3, PAGE(S) 320-324, XP000615980
O'DONOGHUE JA: "Strategies for selective targeting of Auger electron emitters to tumor cells.", J NUCL MED, APR 1996, VOL. 37, NO. 4 SUPPL, PAGE(S) 3S-6S, XP002024863
KAIREMO KJ ET AL: "Oligoradionuclidetherapy using radiolabelled antisense oligodeoxynucleotide phosphorothioates.", ANTICANCER DRUG DES, SEP 1996, VOL. 11, NO. 6, PAGE(S) 439-49, XP000615940
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