CONOTOXIN POLYPEPTIDE Κ-CPTX-BT102, AND METHOD FOR PREPARATION THEREOF AND APPLICATION THEREOF

Title:

CONOTOXIN POLYPEPTIDE Κ-CPTX-BT102, AND METHOD FOR PREPARATION THEREOF AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2016/049869

Kind Code:

A1

Abstract:

Disclosed are a conotoxin polypeptide κ-CPTx-bt102, a method for preparation thereof, and an application thereof. The conotoxin polypeptide of the present invention consists of 15 amino acids, has a molecular weight of 1660.61 daltons, and has the full sequence RCRCEQTCGTCVPCC.

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Inventors:

LIN ZHILONG (CN)
WEN BO (CN)
TONG TING (CN)
LIU JIE (CN)
DU CHAOQIN (CN)
MO FEN (CN)
PENG CHAO (CN)
SHI QIONG (CN)

Application Number:

PCT/CN2014/087978

Publication Date:

April 07, 2016

Filing Date:

September 30, 2014

Export Citation:

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Assignee:

BGI SHENZHEN CO LTD (CN)

International Classes:

C07K7/08; A61K38/10; A61P9/00; A61P21/00; A61P25/08; A61P25/16; A61P25/24; A61P25/28; A61P29/00; A61P35/00; C07K1/00

Domestic Patent References:

WO1997034925A1

1997-09-25

Foreign References:

CN102190708A

2011-09-21

Other References:

FAN, CX ET AL.: "A novel conotoxin from Conus betulinus, kappa-BtX, unique in cysteine pattern and in function as a specific BK channel modulator", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 278, no. 15, 11 April 2003 (2003-04-11), pages 12624 - 12633, XP055366962, ISSN: 0021-9258
See also references of EP 3202776A4

Attorney, Agent or Firm:

SHENZHEN KEJIN INTELLECTUAL PROPERTY OFFICE (CN)
深圳市科进知识产权代理事务所(普通合伙) (CN)

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