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Title:
CONSTRUCTION AND APPLICATION OF MIRNA-21 OVEREXPRESSING VECTOR
Document Type and Number:
WIPO Patent Application WO/2019/227253
Kind Code:
A1
Abstract:
Provided are a miR-21 overexpressing recombinant vector and a construction method therefor and an application thereof. The function of miR-21 in tumors is studied by constructing a miR-21 overexpressing recombinant vector and overexpressing same in HepG2 cells.

Inventors:
MAO JIYAN (CN)
Application Number:
PCT/CN2018/088528
Publication Date:
December 05, 2019
Filing Date:
May 26, 2018
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Assignee:
SHENZHEN BIOCAN TECH CO LTD (CN)
International Classes:
C12N15/63; C12N15/67
Domestic Patent References:
WO2014159633A12014-10-02
Foreign References:
CN105878264A2016-08-24
Other References:
JIANG, BIN: "Practical Study on Technology of Construction of MicroRNA Overexpression Vector", EXPERIMENTAL TECHNOLOGY AND MANAGEMENT, vol. 31, no. 1, 20 January 2014 (2014-01-20), pages 41 - 44, ISSN: 1002-4956
JIANG, JINGHANG ET AL.: "Overexpression of Microrna-21 Strengthens Stem Cell -Like Characteristics in a Hepatocellular Carcinoma Cell Line", WORLD JOURNAL OF SURGICAL ONCOLOGY, vol. 14, 28 October 2016 (2016-10-28), pages 1 - 9, XP055657696, ISSN: 1477-7819
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