Title:
CONTRAST AGENTS
Document Type and Number:
WIPO Patent Application WO2001089584
Kind Code:
A3
Abstract:
This invention relates to contrast agents and the use of these contrast agents for diagnosis of diseases in humans and animals based on mapping of metabolic activity. The contrast agents can be used to identify tissue or cells with metabolic activity or enzymatic activity deviating from the normal. A contrast agent substrate changes pharmacodynamic and/or pharmacokinetic properties upon a chemical modification from a contrast agent substrate to a contrast agent product in a specific enzymatic transformation, thereby detecting areas of disease upon a deviation in the enzyme activity from the normal.
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Inventors:
KLAVENESS JO (NO)
TOLLESHAUG HELGE (NO)
CUTHBERTSON ALAN (NO)
KULSETH MARI ANN (NO)
TOLLESHAUG HELGE (NO)
CUTHBERTSON ALAN (NO)
KULSETH MARI ANN (NO)
Application Number:
PCT/NO2001/000215
Publication Date:
May 02, 2002
Filing Date:
May 23, 2001
Export Citation:
Assignee:
AMERSHAM HEALTH AS (NO)
KLAVENESS JO (NO)
TOLLESHAUG HELGE (NO)
CUTHBERTSON ALAN (NO)
KULSETH MARI ANN (NO)
KLAVENESS JO (NO)
TOLLESHAUG HELGE (NO)
CUTHBERTSON ALAN (NO)
KULSETH MARI ANN (NO)
International Classes:
A61K49/00; A61K51/08; (IPC1-7): A61K49/06; A61K49/04; A61K49/22; A61K49/00; A61K51/00
Domestic Patent References:
| WO1997036619A2 | 1997-10-09 | |||
| WO1999058161A1 | 1999-11-18 |
Foreign References:
| US6036941A | 2000-03-14 | |||
| US4913891A | 1990-04-03 | |||
| DE19717904A1 | 1998-10-29 |
Other References:
DATABASE WPI Section Ch Week 200011, Derwent World Patents Index; Class B04, AN 2000-117397, XP002902224
DATABASE WPI Section Ch Week 199521, Derwent World Patents Index; Class B02, AN 1995-158984, XP002902225
DATABASE WPI Section Ch Week 199521, Derwent World Patents Index; Class B02, AN 1995-158984, XP002902225
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