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Title:
CONTRAST MEDIUM FOR THROMBUS FORMATION
Document Type and Number:
WIPO Patent Application WO/2005/079863
Kind Code:
A1
Abstract:
It is intended to provide a contrast medium for thrombus formation capable of binding specifically to a thrombus, lowering background noise and thus improving the resolution in a contrast examination for thrombus formation; and a method of detecting a thrombus by using the same. A contrast medium for thrombus formation comprising, as the active substance, a substance obtained by labeling a compound capable of binding to GPIIb/IIIa which is selected from among compounds represented by the general formulae (I) to (IV) and physiologically acceptable salts thereof; and a method of detecting a thrombus by using the same.

Inventors:
MURAKAMI YOSHIHIRO (JP)
AOKI TOSHIAKI (JP)
TAKAMATSU HIROYUKI (JP)
NISHIMURA SHINTARO (JP)
OSODA KAZUHIKO (JP)
Application Number:
PCT/JP2005/000308
Publication Date:
September 01, 2005
Filing Date:
January 13, 2005
Export Citation:
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Assignee:
FUJISAWA PHARMACEUTICAL CO (JP)
MURAKAMI YOSHIHIRO (JP)
AOKI TOSHIAKI (JP)
TAKAMATSU HIROYUKI (JP)
NISHIMURA SHINTARO (JP)
OSODA KAZUHIKO (JP)
International Classes:
A61K49/00; A61K51/04; C07C251/24; C07C257/18; C07C317/50; C07D207/04; C07D211/34; C07D211/60; C07D295/18; C07D295/185; (IPC1-7): A61K49/00; A61K51/04; C07C251/24; C07C317/50; C07D207/04; C07D295/18
Domestic Patent References:
WO1994021599A11994-09-29
WO2002055544A22002-07-18
WO2002016333A22002-02-28
Foreign References:
JPH11511120A1999-09-28
JP2001504801A2001-04-10
JP2003503310A2003-01-28
JP2000506524A2000-05-30
JPH11502224A1999-02-23
JP2003523339A2003-08-05
JPH0853415A1996-02-27
JPH08505846A1996-06-25
JPH02235853A1990-09-18
Other References:
See also references of EP 1719529A4
Attorney, Agent or Firm:
Nogawa, Shintaro (Minamimorimachi Park Bldg. 1-3, Nishitenma 5-chome, Kita-ku, Osaka-sh, Osaka 47, JP)
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