Title:
OPENING/CLOSING CONTROL DEVICE FOR TARGET FORCE-SENSITIVE ION CHANNEL THAT GENERATES SOUND WAVE PATTERN BY USING RESONANCE FREQUENCY(IES), AND BRAIN FUNCTION CONTROL DEVICE
Document Type and Number:
WIPO Patent Application WO/2024/058640
Kind Code:
A1
Abstract:
The present invention relates to: an opening/closing control device for a target force-sensitive ion channel on a biological lipid membrane; a brain function control device for noninvasively activating or suppressing a target neural circuit or a neural connection network; a recording medium for transmitting, to a computer, a program used in the device, or a computer-readable recording medium; and a sound wave oscillator driven by means of the program. The present invention generates a sound wave pattern using a resonance frequency(ies) of a specific force-sensitive ion channel of a specific cell in a target body site so as to control the opening/closing of a target force-sensitive ion channel.
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Inventors:
CHEON JINWOO (KR)
LEE JAE-HYUN (KR)
KWAK MINSUK (KR)
LEE JUNG-UK (KR)
KANG SUNGHWI (KR)
CHOI SEO-HYUN (KR)
LEE JAE-HYUN (KR)
KWAK MINSUK (KR)
LEE JUNG-UK (KR)
KANG SUNGHWI (KR)
CHOI SEO-HYUN (KR)
Application Number:
PCT/KR2023/014074
Publication Date:
March 21, 2024
Filing Date:
September 18, 2023
Export Citation:
Assignee:
UIF UNIV INDUSTRY FOUNDATION YONSEI UNIV (KR)
INST BASIC SCIENCE (KR)
INST BASIC SCIENCE (KR)
International Classes:
A61N7/00
Foreign References:
| US8340773B2 | 2012-12-25 | |||
| KR20220117853A | 2022-08-24 |
Other References:
AZADEH SEYEDEH SARA, LORDIFARD PARINAZ, SOHEILIFAR MOHAMMAD HASAN, ESMAEELI DJAVID GHOLAMREZA, KESHMIRI NEGHAB HODA: "Ultrasound and Sonogenetics: A New Perspective for Controlling Cells with Sound", IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, SHAHEED BEHESHTI MEDICAL UNIVERSITY - SCHOOL OF PHARMACY, IR, vol. 20, no. 3, 1 January 2021 (2021-01-01), IR , pages 151 - 160, XP093146166, ISSN: 1735-0328, DOI: 10.22037/ijpr.2021.114868.15079
YOO SANGJIN, MITTELSTEIN DAVID R., HURT ROBERT C., LACROIX JEROME, SHAPIRO MIKHAIL G.: "Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification", NATURE COMMUNICATIONS, NATURE PUBLISHING GROUP, UK, vol. 13, no. 1, UK, XP093146169, ISSN: 2041-1723, DOI: 10.1038/s41467-022-28040-1
AZANZA, M.J. DEL MORAL, A. PEREZ BRUZON, R.N.: "Frequency resonance effect of neurons under low-frequency weak magnetic field", JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 310, no. 2, 16 March 2007 (2007-03-16), AMSTERDAM, NL , pages 2865 - 2867, XP022048776, ISSN: 0304-8853, DOI: 10.1016/j.jmmm.2006.11.078
YOO SANGJIN, MITTELSTEIN DAVID R., HURT ROBERT C., LACROIX JEROME, SHAPIRO MIKHAIL G.: "Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification", NATURE COMMUNICATIONS, NATURE PUBLISHING GROUP, UK, vol. 13, no. 1, UK, XP093146169, ISSN: 2041-1723, DOI: 10.1038/s41467-022-28040-1
AZANZA, M.J. DEL MORAL, A. PEREZ BRUZON, R.N.: "Frequency resonance effect of neurons under low-frequency weak magnetic field", JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 310, no. 2, 16 March 2007 (2007-03-16), AMSTERDAM, NL , pages 2865 - 2867, XP022048776, ISSN: 0304-8853, DOI: 10.1016/j.jmmm.2006.11.078
Attorney, Agent or Firm:
ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)
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