Title:
CONTROL METHOD FOR LIQUID CHROMATOGRAPH MASS SPECTROMETRY DEVICE
Document Type and Number:
WIPO Patent Application WO/2023/054125
Kind Code:
A1
Abstract:
The objective of the present disclosure is to provide a liquid chromatograph mass spectrometry device control method with which it is possible to detect contamination of a mobile phase solvent by foreign matter without employing an internal standard substance. In a liquid chromatograph mass spectrometry device control method according to the present disclosure: a first ratio of a signal strength at a first time point to a signal strength at a second time point during measurement employing a first mobile phase solvent is calculated, and a second ratio of the signal strength at the first time point to the signal strength at the second time point during measurement employing a second mobile phase solvent is calculated; and a determination of whether the second mobile phase solvent is contaminated is made in accordance with an absolute difference between the first ratio and the second ratio (see Fig. 2).
Inventors:
SUGAWARA YUKA (JP)
YASUDA HIROYUKI (JP)
TAMURA RIKU (JP)
TOMA TSUGUNAO (JP)
HASHIMOTO YUICHIRO (JP)
SUGIYAMA MASUYUKI (JP)
YASUDA HIROYUKI (JP)
TAMURA RIKU (JP)
TOMA TSUGUNAO (JP)
HASHIMOTO YUICHIRO (JP)
SUGIYAMA MASUYUKI (JP)
Application Number:
PCT/JP2022/035211
Publication Date:
April 06, 2023
Filing Date:
September 21, 2022
Export Citation:
Assignee:
HITACHI HIGH TECH CORP (JP)
International Classes:
G01N27/62; G01N30/34; G01N30/72; G01N30/86
Domestic Patent References:
| WO2018029847A1 | 2018-02-15 | |||
| WO2009123297A1 | 2009-10-08 | |||
| WO2018003011A1 | 2018-01-04 | |||
| WO2009123297A1 | 2009-10-08 |
Foreign References:
| JP2021521440A | 2021-08-26 |
Other References:
NODA, TAKUMI ET AL.: "Carry-over", 7TH JAPAN BIOANALYSIS FORUM [ONLINE], March 2016 (2016-03-01), pages 1 - 40
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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