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Title:
CONTROLLED LASER TREATMENT FOR NON-INVASIVE TISSUE ALTERATION, TREATMENT AND DIAGNOSTICS WITH MINIMAL COLLATERAL DAMAGE
Document Type and Number:
WIPO Patent Application WO2003079883
Kind Code:
A3
Abstract:
A highly controlled and precise system, device and method for tissue and cellular alteration and treatment below or at surfaces with a laser. The present invention is characterized by ultra low levels of collateral damage as defined by physiologically relevant tests that measure tissue viability. The operation of the present invention is based on spectrally confining the interaction between laser energy and a targeted tissue including an essential element for physiologically relevant tests for monitoring tissue viability.

Inventors:
GALUN EITHAN (IL)
LEWIS AARON (IL)
MANEVITCH ALEXANDRA (IL)
KHATCHATOURIANTS ARTIUM (IL)
HEMO YITZCHAK (IL)
ZEIRA EVELYNE (IL)
Application Number:
PCT/IL2003/000260
Publication Date:
April 15, 2004
Filing Date:
March 27, 2003
Export Citation:
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Assignee:
HADASIT MED RES SERVICE (IL)
YISSUM RES DEV CO (IL)
GALUN EITHAN (IL)
AARON LEWIS (IL)
MANEVITCH ALEXANDRA (IL)
KHATCHATOURIANTS ARTIUM (IL)
HEMO YITZCHAK (IL)
ZEIRA EVELYNE (IL)
International Classes:
A01N43/04; A61B1/06; A61B17/00; A61B18/20; A61K31/70; A61N1/32; C12N15/87; A61B; (IPC1-7): A61B1/06; A61B17/00; A01N43/04; A61K31/70; C12N15/87
Foreign References:
US5658565A1997-08-19
Other References:
WILSON M., MIA N.: "Sensitisation of candida albicans to killing by low-power laser light", JOURNAL OF ORAL PATHOLOGY MEDICINE, vol. 22, 1993, pages 354 - 357, XP002974711
MESSNER C. ET AL: "Generation of tunable, ultrashort THz radiation up to 5.3 THz", SPIE, vol. 3265, 1998, pages 136 - 143, XP002974712
HAGLUND R.F. ET AL: "Surface modification and ablation of insulators using a tunable, picosecond mid-infrared laser", MATERIALS RESEARCH SOCIETY SYMPOSIUM PROCEEDIINGS, vol. 526, 1998, pages 3 - 14, XP002974713
CIULLA T.A. ET AL: "Changing therapeutic paradigms for exudative age-related macular degeneration: antiangiogenic agents and photodynamic therapy", EXPERIMENTAL OPINION INVESTIGATIVE DRUGS, vol. 8, no. 12, 1999, pages 2173 - 2182, XP008014314
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