Title:
CONTROLLED RELEASE IMPLANTABLE DEVICES
Document Type and Number:
WIPO Patent Application WO2001008717
Kind Code:
A9
Abstract:
Implantable devices that deliver a drug to a target location are disclosed. In general, the devices include a portion that engages tissue near the target location and a section with an internal cavity that houses the drug. The drug can be incorporated into a controlled release agent, such as drug-polymer microspheres, which steadily or intermittently release the drug. Alternatively, instead of defining an internal cavity, the section can be formed from a material that includes the controlled release agent. The devices can be used, e.g., to deliver down-regulatory cytokines to a site of inflammation.
Inventors:
BEANE RICHARD (US)
MILLER-GRAZIANO CAROL (US)
EK STEVEN (US)
SIKORA GEORGE (US)
NIEMANN ALLISON (US)
LITWIN DEMETRIUS (US)
MILLER-GRAZIANO CAROL (US)
EK STEVEN (US)
SIKORA GEORGE (US)
NIEMANN ALLISON (US)
LITWIN DEMETRIUS (US)
Application Number:
PCT/US2000/021288
Publication Date:
July 18, 2002
Filing Date:
August 03, 2000
Export Citation:
Assignee:
SMITH & NEPHEW INC (US)
UNIV MASSACHUSETTS (US)
BEANE RICHARD (US)
MILLER-GRAZIANO CAROL (US)
EK STEVEN (US)
SIKORA GEORGE (US)
NIEMANN ALLISON (US)
LITWIN DEMETRIUS (US)
UNIV MASSACHUSETTS (US)
BEANE RICHARD (US)
MILLER-GRAZIANO CAROL (US)
EK STEVEN (US)
SIKORA GEORGE (US)
NIEMANN ALLISON (US)
LITWIN DEMETRIUS (US)
International Classes:
A61K38/00; A61M37/00; A61K38/22; A61K45/00; A61L31/16; A61P29/00; (IPC1-7): A61L31/16
Download PDF:
Previous Patent: METHOD OF PRESERVATION OF AMNION AND USES THEREOF
Next Patent: BLOOD TREATMENT SYSTEM PROVIDING PULSATILE FLOW AND METHOD OF USE
Next Patent: BLOOD TREATMENT SYSTEM PROVIDING PULSATILE FLOW AND METHOD OF USE