Title:
CONTROLLED-RELEASED PEPTIDE FORMULATIONS
Document Type and Number:
WIPO Patent Application WO/2010/025435
Kind Code:
A3
Abstract:
Described herein are methods and compositions for modulating the release and/or drug loading characteristics of encapsulated bioactive agents in polymer-based delivery systems via direct modification of the isoelectric point and/or net charge of the bioactive agent.
Inventors:
BURTON KEVIN (US)
WOEHR TORSTEN (US)
TICE THOMAS R (US)
AYOUB MIMOUN (CH)
WOEHR TORSTEN (US)
TICE THOMAS R (US)
AYOUB MIMOUN (CH)
Application Number:
PCT/US2009/055461
Publication Date:
November 24, 2011
Filing Date:
August 28, 2009
Export Citation:
Assignee:
GENZYME CORP (US)
BURTON KEVIN (US)
WOEHR TORSTEN (US)
TICE THOMAS R (US)
AYOUB MIMOUN (CH)
BURTON KEVIN (US)
WOEHR TORSTEN (US)
TICE THOMAS R (US)
AYOUB MIMOUN (CH)
International Classes:
A61K9/16; A61K38/00; A61K38/08
Domestic Patent References:
| WO2007084460A2 | 2007-07-26 |
Foreign References:
| US5538739A | 1996-07-23 |
Attorney, Agent or Firm:
LORENZ, Todd, A. (LLPFour Embarcadero Center,Suite 350, San Francsico CA, US)
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