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Title:
COPOLYMER, AS WELL AS SEPARATION MEMBRANE, MEDICAL DEVICE, AND BLOOD PURIFIER IN WHICH SAID COPOLYMER IS USED
Document Type and Number:
WIPO Patent Application WO/2018/025979
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a copolymer having exceptional water permeability, platelet adherence suppression, and protein adherence suppression, and to provide a separation membrane, a medical device, and a medical separation membrane module in which said copolymer is used. The present invention provides a copolymer containing monomer units derived from two or more types of monomer, wherein the hydration energy density of the copolymer is 158.992 to 209.200 kJ・mol‒1・nm‒3, the monomer unit having the highest hydration energy density among the monomer units does not include a hydroxy group, the volume fraction of monomer units having the highest hydration energy density among the monomer units is 35 to 90%, and the difference in hydration energy density is 71.128 to 418.400 kJ・mol‒1・nm‒3.

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Inventors:
BABA, Takeshi (Toray Industries Inc., 1-1, Sonoyama 1-chome, Otsu-sh, Shiga 58, 〒5208558, JP)
KAWAKAMI, Tomonori (Toray Industries Inc., 1-1, Sonoyama 1-chome, Otsu-sh, Shiga 58, 〒5208558, JP)
USHIRO, Suguru (Toray Industries Inc., 1-1, Sonoyama 1-chome, Otsu-sh, Shiga 58, 〒5208558, JP)
UENO, Yoshiyuki (Toray Industries Inc., 1-1, Sonoyama 1-chome, Otsu-sh, Shiga 58, 〒5208558, JP)
Application Number:
JP2017/028339
Publication Date:
February 08, 2018
Filing Date:
August 04, 2017
Export Citation:
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Assignee:
TORAY INDUSTRIES, INC. (1-1 Nihonbashi-Muromachi 2-chome, Chuo-ku Tokyo, 66, 〒1038666, JP)
International Classes:
C08F218/04; A61L33/06; A61M1/16; B01D71/38; B01D71/40; B01D71/44; C08F220/12; C08F226/02; C08F226/10
Domestic Patent References:
WO2012176841A12012-12-27
WO2016158388A12016-10-06
Foreign References:
JP2006518420A2006-08-10
JPS51137677A1976-11-27
JPH03286774A1991-12-17
JPH0218695B21990-04-26
JPH08131791A1996-05-28
JPH06238139A1994-08-30
JP2011072987A2011-04-14
Other References:
TIJINK,M. ET AL.: "Development of novel membranes for blood purification therapies based on copolymers of N-vinylpyrrolidone and n-butylmethacrylate", JOURNAL OF MATERIALS CHEMISTRY B, vol. 1, no. 44, 2013, pages 6066 - 6077, XP055561240, ISSN: 2050-7518
KAZUNORI KATAOKA ET AL.: "Nano Bioengineering", October 2007, pages: 115 - 116
HIDEMUNE NAITO: "Biocompatibility of Dialytic Membrane", 25 March 2010, TOKYO IGAKUSHA LTD., pages: 19
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