Title:
COPOLYMER LIBRARIES AND PRODUCTION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO2003046054
Kind Code:
A3
Abstract:
Combinatorial libraries and methods of making and using same are disclosed, wherein each combinatorial library includes at least three different sublibraries, wherein a sublibrary includes a mixture of copolymers that have the same polymer backbone and at least two different pendant groups on the polymer backbone. In each of the sublibraries, copolymers differ from each other with respect to the relative amounts of the pendant groups present on the polymer backbone. Each of the at least three sublibraries differs from another sublibrary by the copolymers contained therein having at least one pendant group that is different from the pendant groups of the other sublibraries.
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Inventors:
ANDRIANOV ALEXANDER K
Application Number:
PCT/US2002/038173
Publication Date:
October 23, 2003
Filing Date:
November 26, 2002
Export Citation:
Assignee:
PARALLEL SOLUTIONS INC (US)
International Classes:
C07B61/00; C08G77/00; C08G79/02; C08G79/025; C08L85/02; G01N33/44; (IPC1-7): C08G79/02; C07B61/00; C08L83/04; C08L83/10; C08L83/16; C08L85/02
Foreign References:
| US5562909A | 1996-10-08 | |||
| US5869016A | 1999-02-09 | |||
| US6077916A | 2000-06-20 | |||
| US3804881A | 1974-04-16 | |||
| US5644007A | 1997-07-01 |
Other References:
ALLCOCK H R ET AL: "CONTROLLED FORMATION OF CARBOXYLIC ACID GROUPS AT POLYPHOSPHAZENE SURFACES: OXIDATIVE AND HYDROLYTIC ROUTES", CHEMISTRY OF MATERIALS, AMERICAN CHEMICAL SOCIETY, WASHINGTON, US, vol. 8, no. 12, 1 December 1996 (1996-12-01), pages 2730 - 2738, XP000683959, ISSN: 0897-4756
BROCCHINI S ET AL: "A COMBINATORIAL APPROACH FOR POLYMER DESIGN. '", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 119, 14 May 1997 (1997-05-14), pages 4553 - 4554, XP002921376, ISSN: 0002-7863
BROCCHINI S ET AL: "Structure-property correlations in a combinatorial library of degradable biomaterials", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH 1998 UNITED STATES, vol. 42, no. 1, 1998, pages 66 - 75, XP008019552, ISSN: 0021-9304
DICKINSON T A ET AL: "GENERATING SENSOR DIVERSITY THROUGH COMBINATORIAL POLYMER SYNTHESIS", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 69, no. 17, 1 September 1997 (1997-09-01), pages 3413 - 3418, XP000720847, ISSN: 0003-2700
ALAKHOV V PIETRZYNSKI G & KABANOV A: "Combinatorial approaches to formulation development", CURRENT OPINION IN DRUG DISCOVERY AND DEVELOPMENT, CURRENT DRUGS, LONDON, GB, vol. 4, no. 4, July 2001 (2001-07-01), pages 493 - 501, XP002958137, ISSN: 1367-6733
COWIE J M G ET AL: "ION CONDUCTION IN MIXTURES OF SALTS AND POLYPHOSPHAZENES WITH PENDANT 16-CROWN-5 ETHER GROUPS", MAKROMOLEKULARE CHEMIE, RAPID COMMUNICATIONS, HUTHIG UND WEPF VERLAG. BASEL, CH, vol. 9, no. 6, 1 June 1988 (1988-06-01), pages 387 - 391, XP000024517
DATABASE WPI Section Ch Week 199630, Derwent World Patents Index; Class A18, AN 1996-295559, XP002247536
BROCCHINI S ET AL: "A COMBINATORIAL APPROACH FOR POLYMER DESIGN. '", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 119, 14 May 1997 (1997-05-14), pages 4553 - 4554, XP002921376, ISSN: 0002-7863
BROCCHINI S ET AL: "Structure-property correlations in a combinatorial library of degradable biomaterials", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH 1998 UNITED STATES, vol. 42, no. 1, 1998, pages 66 - 75, XP008019552, ISSN: 0021-9304
DICKINSON T A ET AL: "GENERATING SENSOR DIVERSITY THROUGH COMBINATORIAL POLYMER SYNTHESIS", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 69, no. 17, 1 September 1997 (1997-09-01), pages 3413 - 3418, XP000720847, ISSN: 0003-2700
ALAKHOV V PIETRZYNSKI G & KABANOV A: "Combinatorial approaches to formulation development", CURRENT OPINION IN DRUG DISCOVERY AND DEVELOPMENT, CURRENT DRUGS, LONDON, GB, vol. 4, no. 4, July 2001 (2001-07-01), pages 493 - 501, XP002958137, ISSN: 1367-6733
COWIE J M G ET AL: "ION CONDUCTION IN MIXTURES OF SALTS AND POLYPHOSPHAZENES WITH PENDANT 16-CROWN-5 ETHER GROUPS", MAKROMOLEKULARE CHEMIE, RAPID COMMUNICATIONS, HUTHIG UND WEPF VERLAG. BASEL, CH, vol. 9, no. 6, 1 June 1988 (1988-06-01), pages 387 - 391, XP000024517
DATABASE WPI Section Ch Week 199630, Derwent World Patents Index; Class A18, AN 1996-295559, XP002247536
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