Title:
CORYNEBACTERIUM SP. TRANSFORMED WITH A FRUCTOKINASE GENE DERIVED FROM ESCHERICHIA SP. AND PROCESS FOR PREPARING L-AMINO ACID USING THE SAME
Document Type and Number:
WIPO Patent Application WO/2012/134253
Kind Code:
A3
Abstract:
The present invention relates to Corynebacterium sp. that is transformed with an Escherichia sp.-derived fructokinase gene to express fructokinase showing a sufficient activity of converting fructose into fructose-6-phosphate, thereby preventing unnecessary energy consumption, and a method for producing L-amino acids using the strain. The transformed Corynebacterium sp. of the present invention is able to express fructokinase from the Escherichia-derived fructokinase gene to prevent unnecessary energy consumption during fructose metabolism, leading to more cost-effective production of L-amino acids. Therefore, it can be widely used for the effective production of L-amino acids.
Inventors:
BAE HYUN WON (KR)
KIM HYUNG JOON (KR)
MOON JUN OK (KR)
JANG JAE WOO (KR)
KIM JONG CHUL (KR)
KIM TAE HAN (KR)
SUNG JIN SUCK (KR)
LEE KYUNG HAN (KR)
KIM DAE CHEOL (KR)
KIM HYO JIN (KR)
BAE HYUN AE (KR)
LIM SANG JO (KR)
KIM HYUNG JOON (KR)
MOON JUN OK (KR)
JANG JAE WOO (KR)
KIM JONG CHUL (KR)
KIM TAE HAN (KR)
SUNG JIN SUCK (KR)
LEE KYUNG HAN (KR)
KIM DAE CHEOL (KR)
KIM HYO JIN (KR)
BAE HYUN AE (KR)
LIM SANG JO (KR)
Application Number:
PCT/KR2012/002474
Publication Date:
December 27, 2012
Filing Date:
April 02, 2012
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
BAE HYUN WON (KR)
KIM HYUNG JOON (KR)
MOON JUN OK (KR)
JANG JAE WOO (KR)
KIM JONG CHUL (KR)
KIM TAE HAN (KR)
SUNG JIN SUCK (KR)
LEE KYUNG HAN (KR)
KIM DAE CHEOL (KR)
KIM HYO JIN (KR)
BAE HYUN AE (KR)
LIM SANG JO (KR)
BAE HYUN WON (KR)
KIM HYUNG JOON (KR)
MOON JUN OK (KR)
JANG JAE WOO (KR)
KIM JONG CHUL (KR)
KIM TAE HAN (KR)
SUNG JIN SUCK (KR)
LEE KYUNG HAN (KR)
KIM DAE CHEOL (KR)
KIM HYO JIN (KR)
BAE HYUN AE (KR)
LIM SANG JO (KR)
International Classes:
C12N1/21; C12N15/31; C12N15/77; C12P13/04
Foreign References:
| KR100564805B1 | 2006-03-27 | |||
| US7179623B2 | 2007-02-20 | |||
| US20100330624A1 | 2010-12-30 |
Other References:
JUDITH BECKER ET AL.: "Amplified expression of fructose 1,6-bisphosphatase in Corynebacterium glutamicum increases in vivo flux through the pentose phosphate pathway and lysine production on different carbon sources", APPLIED AND ENVIRONMENTAL MICROBIOLOGY., vol. 71, no. 12, December 2005 (2005-12-01), pages 8587 - 8596, XP008148992
DORIS RITTMANN ET AL.: "Engineering of a glycerol utilization pathway for amino acid production by Corynebacterium glutamicum", APPLIED AND ENVIRONMENTAL MICROBIOLOGY., vol. 74, no. 20, October 2008 (2008-10-01), pages 6216 - 6222, XP002578554
STEFFEN N. LINDNER ET AL.: "Impact of a new glucose utilization pathway in amino acid-producing Corynebacterium glutamicum", BIOENGINEERED BUGS., vol. 2, no. 5, 1 September 2011 (2011-09-01), pages 291 - 295, XP055123920
DORIS RITTMANN ET AL.: "Engineering of a glycerol utilization pathway for amino acid production by Corynebacterium glutamicum", APPLIED AND ENVIRONMENTAL MICROBIOLOGY., vol. 74, no. 20, October 2008 (2008-10-01), pages 6216 - 6222, XP002578554
STEFFEN N. LINDNER ET AL.: "Impact of a new glucose utilization pathway in amino acid-producing Corynebacterium glutamicum", BIOENGINEERED BUGS., vol. 2, no. 5, 1 September 2011 (2011-09-01), pages 291 - 295, XP055123920
Attorney, Agent or Firm:
SON, Min (6th Floor City Air Tower,36, Teheran-ro 87 gil, Samsung-dong, Gangnam-gu, Seoul 135-973, KR)
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