Title:
CORYNEFORM BACTERIAL TRANSFORMANT AND METHOD FOR PRODUCING 4-AMINOBENZOIC ACID OR SALT THEREOF USING SAME
Document Type and Number:
WIPO Patent Application WO/2017/146241
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a microorganism capable of efficiently producing para-aminobenzoic acid (4-ABA) or a salt thereof using a saccharide as the starting material, and a method for efficiently producing 4-ABA or a salt thereof using the microorganism. A transformant is obtained by introducing the gene encoding 4-amino-4-deoxychorismate lyase, gene encoding para-aminobenzoic acid synthetase component I, and gene encoding para-aminobenzoic acid synthetase component II to coryneform bacteria, and the transformant is capable of efficiently producing 4-ABA or a salt thereof from a saccharide.
Inventors:
INUI MASAYUKI
HIRAGA KAZUMI
SUDA MASAKO
KUBOTA TAKESHI
HIRAGA KAZUMI
SUDA MASAKO
KUBOTA TAKESHI
Application Number:
PCT/JP2017/007232
Publication Date:
August 31, 2017
Filing Date:
February 24, 2017
Export Citation:
Assignee:
RES INST OF INNOVATIVE TECH FOR THE EARTH (JP)
SUMITOMO BAKELITE CO (JP)
SUMITOMO BAKELITE CO (JP)
International Classes:
C12N15/09; C12N1/21; C12P13/02
Domestic Patent References:
WO2013103894A1 | 2013-07-11 | |||
WO2016027870A1 | 2016-02-25 | |||
WO2015124687A1 | 2015-08-27 |
Foreign References:
JP2015000015A | 2015-01-05 |
Other References:
KUBOTA, T. ET AL.: "Production of para- aminobenzoate by genetically engineered Corynebacterium glutamicum and non-biological formation of an N-glucosyl byproduct.", METABOLIC ENGINEERING, vol. 38, 26 July 2016 (2016-07-26), pages 322 - 330, XP029804987
See also references of EP 3421599A4
See also references of EP 3421599A4
Attorney, Agent or Firm:
IKEUCHI SATO & PARTNER PATENT ATTORNEYS (JP)
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