Title:
COSMETIC METHOD AND DERMATOLOGICAL TOPICAL AGENT FOR USE THEREIN, MIGRATION IMPARTING AGENT, AND METHOD FOR SCREENING COMPONENTS FOR USE IN COSMETIC METHOD FOR IMPROVING SKIN STATE
Document Type and Number:
WIPO Patent Application WO/2016/194760
Kind Code:
A1
Abstract:
The present invention pertains to a cosmetic method for applying a migration imparting agent for adipose-derived stem cells to the skin and thereby causing adipose-derived stem cells to migrate to the dermis to improve the skin state. The present invention also pertains to a dermatological topical agent for use in the abovementioned cosmetic method, and is characterized by containing a migration imparting agent which is applied to the skin to cause adipose-derived stem cells to migrate to the dermis. The present invention further pertains to a migration imparting agent for adipose-derived stem cells which contains a polyol compound and at least one hydrophilic biological substance. The present invention also pertains to a method for screening components for use in a cosmetic method for improving the skin state, the screening method comprising a step for evaluating the migration activity of adipose-derived stem cells using a formulated medium containing a sample.
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Inventors:
TSUDA TOMOHIRO (JP)
YUMOTO MASAYO (JP)
YUMOTO MASAYO (JP)
Application Number:
PCT/JP2016/065560
Publication Date:
December 08, 2016
Filing Date:
May 26, 2016
Export Citation:
Assignee:
ROHTO PHARMA (JP)
International Classes:
A61K8/39; A61K8/34; A61K8/60; A61K8/64; A61K8/65; A61K8/73; A61K31/047; A61K31/7004; A61K31/7016; A61K31/702; A61K31/715; A61K31/726; A61K38/00; A61K38/17; A61K45/00; A61P17/00; A61P43/00; A61Q19/00
Domestic Patent References:
| WO2009138801A2 | 2009-11-19 | |||
| WO2012036211A1 | 2012-03-22 |
Foreign References:
| JP2014214094A | 2014-11-17 | |||
| JP2013507956A | 2013-03-07 | |||
| JPH01207220A | 1989-08-21 | |||
| JPH07285844A | 1995-10-31 | |||
| JP2010077046A | 2010-04-08 | |||
| JP2009539546A | 2009-11-19 | |||
| JP2009538917A | 2009-11-12 |
Other References:
PIKART, L. ET AL.: "GHK-Copper Peptide in skin Remodeling and Anti-aging", SOFW JOURNAL, vol. 136, no. 6, June 2010 (2010-06-01), pages 10,12 - 14,16-18,20, ISSN: 0942-7694
KIM, WON-SERK ET AL.: "Antiwrinkle effect of adipose-derived stem cell : Activation of dermal fibroblast by secretory factors", JOURNAL OF DERMATOLGICAL SCIENCE, vol. 53, no. 2, 2009, pages 96 - 102, XP025815305, ISSN: 0923-1811
PARK, BYUNG-SOON ET AL.: "Adipose-Derived Stem Cells and Their Secretory Factors as a Promising Therapy for Skin Aging", DERMATOLOGIC SURGERY, vol. 34, no. 10, 2008, pages 1323 - 1326, XP002604348, ISSN: 1076-0512
KIM, WON-SERK ET AL.: "Antiwrinkle effect of adipose-derived stem cell : Activation of dermal fibroblast by secretory factors", JOURNAL OF DERMATOLGICAL SCIENCE, vol. 53, no. 2, 2009, pages 96 - 102, XP025815305, ISSN: 0923-1811
PARK, BYUNG-SOON ET AL.: "Adipose-Derived Stem Cells and Their Secretory Factors as a Promising Therapy for Skin Aging", DERMATOLOGIC SURGERY, vol. 34, no. 10, 2008, pages 1323 - 1326, XP002604348, ISSN: 1076-0512
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
Yoshiki Hasegawa (JP)
Yoshiki Hasegawa (JP)
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