Title:
COUMARINS EXTRACTIONS AND THEIR USES FOR TREATING HYPERTENSION DISEASE
Document Type and Number:
WIPO Patent Application WO/2003/075938
Kind Code:
A1
Abstract:
The invention relates to a kind of Coumarin Extraction coming from Chinese herbs and containing Imperatorin and Isoimperatorin. The invention also relates to a use of the extraction for treating hypertension disease. Especially, the invention provides a kind of Coumarin extraction coming from Angelica dahurica. Furthermore the invention also provides an extract method adopted by the invention, which is Super-critical CO2 Extraction. The invention also provides a pharmaceutical composition containing the extraction. The extract method of the invention is simple and practical, the extraction has a good purity, and the formula of the invention is unique, but also the pharmaceutical composition containing the extraction has a new use for treating hypertension disease.
Inventors:
HE LANGCHONG (CN)
YANG GUANGDE (CN)
CAO YONGXIAO (CN)
LI XILING (CN)
LIANG MINGJIN (CN)
MA YING (CN)
HE WEI (CN)
HUANG YI (CN)
YANG GUANGDE (CN)
CAO YONGXIAO (CN)
LI XILING (CN)
LIANG MINGJIN (CN)
MA YING (CN)
HE WEI (CN)
HUANG YI (CN)
Application Number:
PCT/CN2003/000167
Publication Date:
September 18, 2003
Filing Date:
March 06, 2003
Export Citation:
Assignee:
BEIJING TONGYUAN PHARMACEUTICA (CN)
HE LANGCHONG (CN)
YANG GUANGDE (CN)
CAO YONGXIAO (CN)
LI XILING (CN)
LIANG MINGJIN (CN)
MA YING (CN)
HE WEI (CN)
HUANG YI (CN)
HE LANGCHONG (CN)
YANG GUANGDE (CN)
CAO YONGXIAO (CN)
LI XILING (CN)
LIANG MINGJIN (CN)
MA YING (CN)
HE WEI (CN)
HUANG YI (CN)
International Classes:
A61K31/37; A61K36/232; A61P9/12; B01D11/02; C07D493/04; (IPC1-7): A61K35/78; A61P9/12
Other References:
ZHOU JIMING ET AL.: "Research for angelica dahurica Benth. Et Hook", CHINESE HOSPITAL PHARMACEUTICAL MEDICINE, vol. 8, no. 11, 1988, pages 2 - 6
LING MINGJIN ET AL.: "Research for extraction imperatorin from Angelica dahurica Benth. Et Hook", CHINESE PHARMACIST-PREPARED MEDICINE, vol. 22, no. 12, 2000, pages 147 - 148
LING MINGJIN ET AL.: "Research for extraction imperatorin from Angelica dahurica Benth. Et Hook", CHINESE PHARMACIST-PREPARED MEDICINE, vol. 22, no. 12, 2000, pages 147 - 148
Attorney, Agent or Firm:
BEIJING SANYOU INTELLECTUAL PROPERTY AGENT LTD. (8 Beijing, CN)
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