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Title:
THE CREAM CONTAINING INTERFERON LIPOSOME
Document Type and Number:
WIPO Patent Application WO/2005/074892
Kind Code:
A1
Abstract:
The invention relates to a cream containing interferon liposome, which comprises the components as follows: the interferon that be encapsulated in the liposome; and the matrix of the cream. The advantages of the inventive interferon­containing liposome is high encapsulation ratio, good stabilization of manufacture, good uniformity, stable pharmacologic effects, and low leakage ratio. It can enhance the encapsulation of the liposome and increase the activity of the interferon and the pharmacodynamics by formulating the interferon liposome and the matrix into cream. It can treat the dermal diseases caused by virus infection,such as herpes zoster, herpetic stomatitis, wart, acute condyloma, infection molluscum, aedea herpes, flat wart, common wart, genital ulcer, aphtha and itching and the like.

Inventors:
WANG YAN (CN)
CHAI XIANGDONG (CN)
LI YUNFU (CN)
DONG BAOKE (CN)
ZHANG XUETAO (CN)
Application Number:
PCT/CN2004/000803
Publication Date:
August 18, 2005
Filing Date:
July 13, 2004
Export Citation:
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Assignee:
SHENZHEN NEPTUNUS INTERLONG BI (CN)
WANG YAN (CN)
CHAI XIANGDONG (CN)
LI YUNFU (CN)
DONG BAOKE (CN)
ZHANG XUETAO (CN)
International Classes:
A61K9/127; A61K38/21; A61K47/06; A61K47/10; A61K47/14; A61K47/26; (IPC1-7): A61K9/127; A61K38/21; A61P31/12
Domestic Patent References:
WO2003030865A12003-04-17
Foreign References:
US5853755A1998-12-29
CN1200942A1998-12-09
RU2176518C12001-12-10
JPH01290634A1989-11-22
JPH06228012A1994-08-16
JPS62283934A1987-12-09
CN1200941A1998-12-09
Other References:
YANG XINJIAN ET AL: "The preparation of the dermal formulation of the interferon liposome.", TIANJING PHARMACEUTICAL., vol. 14, no. 6, December 2002 (2002-12-01), pages 42 - 43
Attorney, Agent or Firm:
LECOME INTELLECTUAL PROPERTY AGENT LTD. (3/F Quantum Silver Plaza, No.23 Zhichun R, Haidian District Beijing 3, CN)
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