Title:
CROSS-LINKED ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE FOR USE AS MEDICAL IMPLANT
Document Type and Number:
WIPO Patent Application WO2002068006
Kind Code:
A3
Abstract:
The present invention relates to the prevention and decrease of osteolysis produced by wear of the ultrahigh molecular weight polyethylene (UHMWPE). Methods are disclosed for the isolation of wear particles, preparation of implants exhibiting decreased wear in comparison to conventional UHMWPE and preparation of implants that cause decreased biological response in comparison to conventional UHMWPE. The implants created by these methods are also included in the present invention.
Inventors:
SCOTT MARCUS LEE (US)
JANI SHILESH CHANDRAKANT (US)
JANI SHILESH CHANDRAKANT (US)
Application Number:
PCT/US2002/005511
Publication Date:
January 03, 2003
Filing Date:
February 25, 2002
Export Citation:
Assignee:
SMITH & NEPHEW INC (US)
SCOTT MARCUS LEE (US)
JANI SHILESH CHANDRAKANT (US)
SCOTT MARCUS LEE (US)
JANI SHILESH CHANDRAKANT (US)
International Classes:
A61F2/30; A61L27/16; A61L27/00; A61L27/50; (IPC1-7): A61L27/16; A61L27/50
Domestic Patent References:
| WO1997029793A1 | 1997-08-21 | |||
| WO1998014223A1 | 1998-04-09 | |||
| WO1996025127A1 | 1996-08-22 |
Other References:
A ET AL: "Comparison of the size and morphology of UHMWPE wear debris produced by a hip joint simulator under serum and water lubricated conditions", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 17, no. 9, 1 May 1996 (1996-05-01), pages 865 - 871, XP004032723, ISSN: 0142-9612
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