Title:
CROSSLINKED GELATIN GEL MULTILAYERED STRUCTURE, CARRIER FOR BIOACTIVE FACTOR, PREPARATION FOR RELEASE OF BIOACTIVE FACTOR, AND THEIR PRODUCTION METHODS
Document Type and Number:
WIPO Patent Application WO/2008/016163
Kind Code:
A1
Abstract:
Disclosed is a crosslinked gelatin gel multilayered structure having a layered structure comprising multiple crosslinked gelatin gel layers arranged adjacent to one another, wherein each of the crosslinked gelatin gel layers is produced by crosslinking gelatin or a gelatin derivative by irradiation with electron beam in an oxygen-containing atmosphere. Also disclosed is a preparation for releasing a bioactive factor, which comprises the crosslinked gelatin gel multilayered structure and the bioactive factor contained in the crosslinked gelatin gel multilayered structure. Further disclosed are a method for producing the multilayered structure and a method for producing the preparation.
Inventors:
ISHIGURO TOMOYUKI (JP)
FUKANO KENJI (JP)
TABATA YASUHIKO (JP)
FUKANO KENJI (JP)
TABATA YASUHIKO (JP)
Application Number:
PCT/JP2007/065323
Publication Date:
February 07, 2008
Filing Date:
July 31, 2007
Export Citation:
Assignee:
NICHIBAN KK (JP)
UNIV KYOTO (JP)
ISHIGURO TOMOYUKI (JP)
FUKANO KENJI (JP)
TABATA YASUHIKO (JP)
UNIV KYOTO (JP)
ISHIGURO TOMOYUKI (JP)
FUKANO KENJI (JP)
TABATA YASUHIKO (JP)
International Classes:
A61K47/42; A61K38/22; B32B9/02
Foreign References:
| JPH06500802A | 1994-01-27 | |||
| JPS579711A | 1982-01-19 | |||
| JP2005263759A | 2005-09-29 | |||
| US6831058B1 | 2004-12-14 | |||
| US5618312A | 1997-04-08 |
Other References:
KIMURA Y. ET AL.: "Denshisen Kakyo ni yoru Enkisei Sen'i Mesaibo Zoshoku Inshi Johotai no Sakusei to sono Kekkan Shinsei Koka", POLYMER PREPRINTS, JAPAN (CD-ROM), 10 May 2006 (2006-05-10), pages 1922, XP003020905
KIMURA Y. ET AL.: "Shushu no Kakyo Hoho o Mochiita Saibo Zoshoku Inshi no Joho no tameno Gelatin Hydrogel no Sakusei", THE SOCIETY OF POLYMER SCIENCE, JAPAN PREPRINTS OF RESEARCH GROUP ON BIOMEDICAL POLYMER SYMPOSIUM, vol. 34TH, 1 August 2005 (2005-08-01), pages 19 - 20, XP003020906
See also references of EP 2052740A4
KIMURA Y. ET AL.: "Shushu no Kakyo Hoho o Mochiita Saibo Zoshoku Inshi no Joho no tameno Gelatin Hydrogel no Sakusei", THE SOCIETY OF POLYMER SCIENCE, JAPAN PREPRINTS OF RESEARCH GROUP ON BIOMEDICAL POLYMER SYMPOSIUM, vol. 34TH, 1 August 2005 (2005-08-01), pages 19 - 20, XP003020906
See also references of EP 2052740A4
Attorney, Agent or Firm:
NISHIKAWA, Shigeaki et al. (43-9Higashi-Nippori 3-chome,Arakawa-k, Tokyo 14, JP)
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