Title:
CRYSTAL FORM OF BREXPIPRAZOLE AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2017/194002
Kind Code:
A1
Abstract:
Disclosed are a crystal form of Brexpiprazole and a preparation method therefor. The X-ray powder diffraction pattern, which is detected with Cu-K α radiation, of the crystal form of Brexpiprazole has characteristic peaks at the positions where 2θ is about 9.1±0.2, 15.2±0.2, 15.7±0.2, 17.6±0.2, 18.1±0.2, and 24.4±0.2. The crystal form I of Brexpiprazole has a high purity, good stability and good reproducibility, and is suitable for industrial production.
Inventors:
JIAO YINGLU (CN)
LI HANDA (CN)
WANG BOYU (CN)
HUANG LUNING (CN)
CHEN XI (CN)
GU HONG (CN)
LI HANDA (CN)
WANG BOYU (CN)
HUANG LUNING (CN)
CHEN XI (CN)
GU HONG (CN)
Application Number:
PCT/CN2017/084171
Publication Date:
November 16, 2017
Filing Date:
May 12, 2017
Export Citation:
Assignee:
ZHEJIANG HUAHAI PHARM CO LTD (CN)
SHANGHAI AOBO PHARMTECH INC LTD (CN)
SHANGHAI AOBO PHARMTECH INC LTD (CN)
International Classes:
C07D409/12
Foreign References:
CN104254530A | 2014-12-31 | |||
CN101155804A | 2008-04-02 | |||
CN103717587A | 2014-04-09 | |||
CN105461703A | 2016-04-06 | |||
CN104829602A | 2015-08-12 | |||
CN104844585A | 2015-08-19 | |||
CN105061414A | 2015-11-18 | |||
CN105175401A | 2015-12-23 | |||
CN105461704A | 2016-04-06 |
Other References:
See also references of EP 3444248A4
Attorney, Agent or Firm:
PATENTSINO IP FIRM (CN)
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