Title:
CRYSTAL FORM A OF MILBEMYCIN A3 OXIME AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2018/006792
Kind Code:
A1
Abstract:
The present invention relates to the field of pharmaceuticals, especially to the field of veterinary drugs, and more particularly to a crystal form of milbemycin A3 oxime, able to be characterized by the X-ray powder diffraction spectrogram, infrared absorption (IR) spectrogram, differential scanning calorimetry (DSC), and thermogravimetric analysis (TGA), etc. Furthermore, the present invention also relates to a method for preparing the crystal form of milbemycin A3 oxime and to a use of the crystal form of milbemycin A3 oxime as an insecticidal and acaricidal agent.
Inventors:
TENG YUN (CN)
XU HONGBING (CN)
JIANG LIANQING (CN)
CHEN ZHENGJIE (CN)
BAI HUA (CN)
XU HONGBING (CN)
JIANG LIANQING (CN)
CHEN ZHENGJIE (CN)
BAI HUA (CN)
Application Number:
PCT/CN2017/091624
Publication Date:
January 11, 2018
Filing Date:
July 04, 2017
Export Citation:
Assignee:
ZHEJIANG HISUN PHARM CO LTD (CN)
International Classes:
C07D493/22; A01N43/90; A01P7/02; A01P7/04
Foreign References:
| CN104327094A | 2015-02-04 | |||
| CN105440049A | 2016-03-30 | |||
| CN106148216A | 2016-11-23 | |||
| JP2000281683A | 2000-10-10 | |||
| CN105061457A | 2015-11-18 | |||
| JPH01197487A | 1989-08-09 | |||
| EP0240274A2 | 1987-10-07 | |||
| US3950360A | 1976-04-13 | |||
| CN201410606012A | 2014-10-30 |
Other References:
XU QIAN-QIAN ET AL.: "Research Progress on Milbemycin Oxime", CHINESE JOURNAL OF VETERINARY DRUG, vol. 43, no. 7, 20 July 2009 (2009-07-20), pages 33 - 36, XP055588215
BIZDENA, E. ET AL.: "X-ray structure analysis of a solid solution of milbemycins A3 and A4", NATURAL PRODUCT RESEARCH, vol. 27, no. 20, 1 May 2013 (2013-05-01), pages 1936 - 1939, XP055562147
See also references of EP 3483165A4
BIZDENA, E. ET AL.: "X-ray structure analysis of a solid solution of milbemycins A3 and A4", NATURAL PRODUCT RESEARCH, vol. 27, no. 20, 1 May 2013 (2013-05-01), pages 1936 - 1939, XP055562147
See also references of EP 3483165A4
Attorney, Agent or Firm:
BOSS & YOUNG PATENT AND TRADEMARK LAW OFFICE (CN)
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